N-Formylmethionine Leucyl-Phenylalanine
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"N-Formylmethionine Leucyl-Phenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D009240
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						| MeSH Number(s) | 
						
							 D02.886.030.676.450.440 D12.125.072.050.685.445 D12.125.142.666.500 D12.125.166.676.450.440 D12.644.456.400 D23.125.685 
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						| Concept/Terms | 
						
							N-Formylmethionine Leucyl-Phenylalanine- N-Formylmethionine Leucyl-Phenylalanine
 - Leucyl-Phenylalanine, N-Formylmethionine
 - N Formylmethionine Leucyl Phenylalanine
 - Formylmethionyl-Leucyl-Phenylalanine
 - Formylmethionyl Leucyl Phenylalanine
 - N-Formyl-Methionyl-Leucyl-Phenylalanine
 - N Formyl Methionyl Leucyl Phenylalanine
 - Formylmet-Leu-Phe
 - Formylmet Leu Phe
 - Formylmethionylleucylphenylalanine
 
  Formylmethionyl Peptide- Formylmethionyl Peptide
 - Peptide, Formylmethionyl
 - N-Formylated Peptide
 - N Formylated Peptide
 - Peptide, N-Formylated
 
  
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				Below are MeSH descriptors whose meaning is more general than "N-Formylmethionine Leucyl-Phenylalanine".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "N-Formylmethionine Leucyl-Phenylalanine".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in this website by year, and whether "N-Formylmethionine Leucyl-Phenylalanine" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1996 | 0 | 1 | 1 | 
| 1999 | 1 | 0 | 1 | 
| 2001 | 0 | 1 | 1 | 
| 2003 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in Profiles.
						
					
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Inducible expression of tissue inhibitor of metalloproteinases-resistant matrix metalloproteinase-9 on the cell surface of neutrophils. Am J Respir Cell Mol Biol. 2003 Sep; 29(3 Pt 1):283-94.
															
								 
							
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Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins. J Immunol. 2001 Jun 15; 166(12):7534-42.
															
								 
							
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Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin. J Cell Biol. 1999 Mar 08; 144(5):1047-56.
															
								 
							
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Ex vivo effects of macrophage colony-stimulating factor on human monocyte activity against fungal and bacterial pathogens. Cytokine. 1996 Jan; 8(1):42-8.
															
								 
							
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Age-dependent changes in transmembrane signalling: identification of G proteins in human lymphocytes and polymorphonuclear leukocytes. Cell Signal. 1993 Sep; 5(5):593-603.
															
								 
							
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Monocyte chemotactic and activating factor is a potent histamine-releasing factor for human basophils. J Exp Med. 1992 Feb 01; 175(2):489-93.
															
								 
							
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Activation of the lipoxygenase pathway in the methionine enkephalin induced respiratory burst in human polymorphonuclear leukocytes. Life Sci. 1988; 42(22):2299-306.