"Pepstatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
N-acylated oligopeptides isolated from culture filtrates of Actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin.
| Descriptor ID |
D010436
|
| MeSH Number(s) |
D12.644.456.724
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pepstatins".
Below are MeSH descriptors whose meaning is more specific than "Pepstatins".
This graph shows the total number of publications written about "Pepstatins" by people in this website by year, and whether "Pepstatins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pepstatins" by people in Profiles.
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Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds. Biochem Biophys Res Commun. 2012 May 11; 421(3):413-7.
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Calculating proton uptake/release and binding free energy taking into account ionization and conformation changes induced by protein-inhibitor association: application to plasmepsin, cathepsin D and endothiapepsin-pepstatin complexes. Proteins. 2004 Aug 15; 56(3):572-84.
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A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor. J Biol Chem. 2001 Jan 05; 276(1):481-7.