"Acetazolamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Descriptor ID |
D000086
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MeSH Number(s) |
D02.886.675.867.060 D03.383.129.708.867.060
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetazolamide".
Below are MeSH descriptors whose meaning is more specific than "Acetazolamide".
This graph shows the total number of publications written about "Acetazolamide" by people in this website by year, and whether "Acetazolamide" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acetazolamide" by people in Profiles.
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Management of spontaneous cerebrospinal fluid leaks. Int Forum Allergy Rhinol. 2019 03; 9(3):330-331.
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Presumed Pseudotumor Cerebri Syndrome After Withdrawal of Inhaled Glucocorticoids. Pediatrics. 2016 06; 137(6).
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Headache and the pseudotumor cerebri syndrome. Curr Pain Headache Rep. 2014 Sep; 18(9):446.
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Acute mountain sickness, inflammation, and permeability: new insights from a blood biomarker study. J Appl Physiol (1985). 2011 Aug; 111(2):392-9.
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Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. Cancer Invest. 2008 May; 26(4):352-8.
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Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction. Neurology. 1993 Feb; 43(2):353-7.
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Acetazolamide treatment of paroxysmal dystonia in central demyelinating disease. Neurology. 1992 Apr; 42(4):919-21.