"Diazoxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
| Descriptor ID |
D003981
|
| MeSH Number(s) |
D02.886.590.700.135.300 D02.886.655.500.300 D03.633.100.174.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Diazoxide".
Below are MeSH descriptors whose meaning is more specific than "Diazoxide".
This graph shows the total number of publications written about "Diazoxide" by people in this website by year, and whether "Diazoxide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diazoxide" by people in Profiles.
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Cardiac subsarcolemmal and interfibrillar mitochondria display distinct responsiveness to protection by diazoxide. PLoS One. 2012; 7(9):e44667.
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Potassium channel openers are uncoupling protonophores: implication in cardioprotection. FEBS Lett. 2004 Jun 18; 568(1-3):167-70.
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Suppression of human tumor cell proliferation through mitochondrial targeting. FASEB J. 2002 Jul; 16(9):1010-6.
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Restoration of Ca2+-inhibited oxidative phosphorylation in cardiac mitochondria by mitochondrial Ca2+ unloading. Mol Cell Biochem. 2001 Apr; 220(1-2):135-40.
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Diazoxide protects mitochondria from anoxic injury: implications for myopreservation. J Thorac Cardiovasc Surg. 2001 Feb; 121(2):298-306.
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Identification and characterization of glucoresponsive neurons in the enteric nervous system. J Neurosci. 1999 Dec 01; 19(23):10305-17.
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ATP-sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria. J Physiol. 1999 Sep 01; 519 Pt 2:347-60.
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[Comparative clinical study of the antihypertensive effects of urapidil versus diazoxide in patients with severe arterial hypertension]. Lijec Vjesn. 1986 Nov-Dec; 108(11-12):494-6.
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[Diazoxide vs. labetalol: a cross-over comparison of acute effects in hypertensive patients (author's transl)]. Lijec Vjesn. 1980 Nov; 102(11):619-23.