Antidepressive Agents, Tricyclic
"Antidepressive Agents, Tricyclic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
| Descriptor ID |
D000929
|
| MeSH Number(s) |
D27.505.954.427.700.122.055
|
| Concept/Terms |
Antidepressive Agents, Tricyclic- Antidepressive Agents, Tricyclic
- Tricyclic Antidepressive Agents
- Agents, Tricyclic Antidepressive
- Antidepressant Drugs, Tricyclic
- Drugs, Tricyclic Antidepressant
- Tricyclic Antidepressant Drugs
- Antidepressants, Tricyclic
- Tricyclic Antidepressants
|
Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents, Tricyclic".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents, Tricyclic".
This graph shows the total number of publications written about "Antidepressive Agents, Tricyclic" by people in this website by year, and whether "Antidepressive Agents, Tricyclic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antidepressive Agents, Tricyclic" by people in Profiles.
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Distal Esophageal Spasm: A Review. Am J Med. 2018 09; 131(9):1034-1040.
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Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells. Sci Rep. 2017 03 21; 7:44867.
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Tianeptine modulates amygdalar glutamate neurochemistry and synaptic proteins in rats subjected to repeated stress. Exp Neurol. 2013 Mar; 241:184-93.
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Depressive and cardiovascular disease comorbidity in a rat model of social stress: a putative role for corticotropin-releasing factor. Psychopharmacology (Berl). 2012 Jul; 222(2):325-36.
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Seizure threshold in a large sample: implications for stimulus dosing strategies in bilateral electroconvulsive therapy: a report from CORE. J ECT. 2009 Dec; 25(4):232-7.
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Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats. Behav Brain Res. 2009 Jan 30; 197(1):41-4.
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Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. Pharmacol Biochem Behav. 2008 Mar; 89(1):46-53.
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Acute stress-mediated increases in extracellular glutamate levels in the rat amygdala: differential effects of antidepressant treatment. Eur J Neurosci. 2007 May; 25(10):3109-14.
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New insights on the use of desipramine as an inhibitor for acid ceramidase. FEBS Lett. 2006 Aug 21; 580(19):4751-6.
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Brain 5-HT receptor system in the stressed infant rat: implications for vulnerability to substance abuse. Psychoneuroendocrinology. 2002 Jan-Feb; 27(1-2):245-72.