"Polymyxin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
Descriptor ID |
D011112
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MeSH Number(s) |
D04.345.566.780.750 D10.477.750.750 D12.644.050.600.750 D12.644.641.780.750 D12.776.543.695.054.600.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polymyxin B".
Below are MeSH descriptors whose meaning is more specific than "Polymyxin B".
This graph shows the total number of publications written about "Polymyxin B" by people in this website by year, and whether "Polymyxin B" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymyxin B" by people in Profiles.
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Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling. J Clin Invest. 2007 Aug; 117(8):2197-204.
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Comparison of peptidoglycan-polysaccharide and lipopolysaccharide stimulation of Kupffer cells to produce tumor necrosis factor and interleukin-1. Hepatology. 1994 Apr; 19(4):1013-22.
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Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages. Antimicrob Agents Chemother. 1993 Mar; 37(3):393-7.
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Polymyxin B increases TXA2/PGH2 agonist and antagonist affinities in human platelet membranes. Eicosanoids. 1988; 1(1):41-4.
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Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products. J Immunol. 1986 Oct 01; 137(7):2225-31.