"Keratins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
| Descriptor ID |
D007633
|
| MeSH Number(s) |
D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratins".
Below are MeSH descriptors whose meaning is more specific than "Keratins".
This graph shows the total number of publications written about "Keratins" by people in this website by year, and whether "Keratins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 4 | 4 |
| 2004 | 1 | 4 | 5 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Keratins" by people in Profiles.
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Expression of renal cell markers and detection of 3p loss links endolymphatic sac tumor to renal cell carcinoma and warrants careful evaluation to avoid diagnostic pitfalls. Acta Neuropathol Commun. 2018 10 19; 6(1):107.
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Estrogen decreases tight junction protein ZO-1 expression in human primary gut tissues. Clin Immunol. 2017 10; 183:174-180.
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Selective segregation of DNA strands persists in long-label-retaining mammary cells during pregnancy. Breast Cancer Res. 2008; 10(5):R90.
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Epicardial development in the rat: a new perspective. Microsc Microanal. 2006 Oct; 12(5):390-8.
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Establishment of epidermal cell lines derived from the skin of the Atlantic bottlenose dolphin (Tursiops truncatus). Anat Rec A Discov Mol Cell Evol Biol. 2005 Dec; 287(2):1246-55.
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Expression of oncostatin M and its receptors in normal and cirrhotic human liver. J Hepatol. 2005 Nov; 43(5):893-900.
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Formation of bradykinin: a major contributor to the innate inflammatory response. Adv Immunol. 2005; 86:159-208.
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Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13. J Biol Chem. 2004 Dec 03; 279(49):51524-33.
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Pathologic quiz case: a patient with Down syndrome presenting with "idiopathic" pericarditis. Primary pericardial malignant mesothelioma. Arch Pathol Lab Med. 2004 Aug; 128(8):e107-8.
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Creation of a stable mammary tumor cell line that maintains fertility-cycle tumor biology of the parent tumor. In Vitro Cell Dev Biol Anim. 2004 Jul-Aug; 40(7):187-95.