STAT4 Transcription Factor
"STAT4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.
| Descriptor ID |
D050797
|
| MeSH Number(s) |
D12.644.360.024.342.400 D12.776.157.057.186.400 D12.776.476.024.430.400 D12.776.930.840.400
|
| Concept/Terms |
STAT4 Transcription Factor- STAT4 Transcription Factor
- Transcription Factor, STAT4
- Signal Transducer and Activator of Transcription 4
- STAT4 Protein
- Transcription Factor STAT4
|
Below are MeSH descriptors whose meaning is more general than "STAT4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT4 Transcription Factor".
This graph shows the total number of publications written about "STAT4 Transcription Factor" by people in this website by year, and whether "STAT4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "STAT4 Transcription Factor" by people in Profiles.
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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 07 01; 27(13):2392-2404.
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Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43.
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Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet. 2011 Mar; 7(3):e1001323.
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Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans. Ann Rheum Dis. 2010 Apr; 69(4):625-6.
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High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum. 2009 Apr; 60(4):1085-95.
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Downregulation of IL-17 and IL-6 in the central nervous system by glatiramer acetate in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2008 Nov 15; 204(1-2):58-65.
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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet. 2008 Feb; 40(2):204-10.