STAT1 Transcription Factor
"STAT1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.
| Descriptor ID |
D050794
|
| MeSH Number(s) |
D12.644.360.024.303.500.500 D12.644.360.024.342.100 D12.776.157.057.061.500.500 D12.776.157.057.186.100 D12.776.260.513.249.500 D12.776.476.024.386.500.500 D12.776.476.024.430.100 D12.776.930.354.249.500 D12.776.930.840.100
|
| Concept/Terms |
STAT1 Transcription Factor- STAT1 Transcription Factor
- Transcription Factor, STAT1
- Transcription Factor STAT91
- Gamma-Activated Factor, 91 kDa
- Gamma Activated Factor, 91 kDa
- STAT-91 Transcription Factor
- STAT 91 Transcription Factor
- Transcription Factor, STAT-91
- STAT-91 Protein
- STAT 91 Protein
- STAT91 Transcription Factor
- Transcription Factor, STAT91
- STAT1 Protein
- Signal Transducer and Activator of Transcription 1
|
Below are MeSH descriptors whose meaning is more general than "STAT1 Transcription Factor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Adaptor Proteins, Signal Transducing [D12.644.360.024]
- Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.644.360.024.303.500]
- STAT1 Transcription Factor [D12.644.360.024.303.500.500]
- STAT Transcription Factors [D12.644.360.024.342]
- STAT1 Transcription Factor [D12.644.360.024.342.100]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Adaptor Proteins, Signal Transducing [D12.776.157.057]
- Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.157.057.061.500]
- STAT1 Transcription Factor [D12.776.157.057.061.500.500]
- STAT Transcription Factors [D12.776.157.057.186]
- STAT1 Transcription Factor [D12.776.157.057.186.100]
- DNA-Binding Proteins [D12.776.260]
- Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.260.513.249]
- STAT1 Transcription Factor [D12.776.260.513.249.500]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Adaptor Proteins, Signal Transducing [D12.776.476.024]
- Interferon-Stimulated Gene Factor 3 [D12.776.476.024.386]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.476.024.386.500]
- STAT1 Transcription Factor [D12.776.476.024.386.500.500]
- STAT Transcription Factors [D12.776.476.024.430]
- STAT1 Transcription Factor [D12.776.476.024.430.100]
- Transcription Factors [D12.776.930]
- Interferon-Stimulated Gene Factor 3 [D12.776.930.354]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.930.354.249]
- STAT1 Transcription Factor [D12.776.930.354.249.500]
- STAT Transcription Factors [D12.776.930.840]
- STAT1 Transcription Factor [D12.776.930.840.100]
Below are MeSH descriptors whose meaning is more specific than "STAT1 Transcription Factor".
This graph shows the total number of publications written about "STAT1 Transcription Factor" by people in this website by year, and whether "STAT1 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 3 | 0 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 2 | 4 |
To return to the timeline,
click here.
Below are the most recent publications written about "STAT1 Transcription Factor" by people in Profiles.
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Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition. Cells. 2019 11 09; 8(11).
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Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression. Mol Cancer Res. 2019 12; 17(12):2395-2409.
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Critical role of the endogenous renin-angiotensin system in maintaining self-renewal and regeneration potential of epidermal stem cells. Biochim Biophys Acta Mol Basis Dis. 2019 10 01; 1865(10):2647-2656.
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STAT1 signaling shields T cells from NK cell-mediated cytotoxicity. Nat Commun. 2019 02 22; 10(1):912.
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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 07 01; 27(13):2392-2404.
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Artesunate inhibits type I interferon-induced production of macrophage migration inhibitory factor in patients with systemic lupus erythematosus. Lupus. 2017 Jan; 26(1):62-72.
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Inverse correlation of expression of microRNA-140-5p with progression of multiple sclerosis and differentiation of encephalitogenic T helper type 1 cells. Immunology. 2016 Apr; 147(4):488-98.
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STAT1 and NF-?B Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells. Mol Cancer Res. 2016 05; 14(5):482-92.
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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9.
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Vitamin d deficiency in a multiethnic healthy control cohort and altered immune response in vitamin D deficient European-American healthy controls. PLoS One. 2014; 9(4):e94500.