"Chromosome Fragility" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Susceptibility of chromosomes to breakage leading to translocation; CHROMOSOME INVERSION; SEQUENCE DELETION; or other CHROMOSOME BREAKAGE related aberrations.
| Descriptor ID |
D002873
|
| MeSH Number(s) |
C23.550.210.110.180 C23.550.362.180.180 G05.365.590.175.165.180 G05.370.180.180
|
| Concept/Terms |
Chromosome Fragility- Chromosome Fragility
- Fragility, Chromosome
- Chromosomal Fragility
- Fragility, Chromosomal
|
Below are MeSH descriptors whose meaning is more general than "Chromosome Fragility".
Below are MeSH descriptors whose meaning is more specific than "Chromosome Fragility".
This graph shows the total number of publications written about "Chromosome Fragility" by people in this website by year, and whether "Chromosome Fragility" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chromosome Fragility" by people in Profiles.
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Variable levels of chromosomal instability and mitotic spindle checkpoint defects in breast cancer. Am J Pathol. 2002 Aug; 161(2):391-7.
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Detection of chromosome 11q13 breakpoints by interphase fluorescence in situ hybridization. A useful ancillary method for the diagnosis of mantle cell lymphoma. Am J Clin Pathol. 2000 Aug; 114(2):248-57.
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An FHIT tumor suppressor gene? Genes Chromosomes Cancer. 1998 Apr; 21(4):281-9.
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Chromosome 3p14 homozygous deletions and sequence analysis of FRA3B. Hum Mol Genet. 1997 Feb; 6(2):193-203.
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Integrated YAC contig containing the 3p14.2 hereditary renal carcinoma 3;8 translocation breakpoint and the fragile site FRA3B. Genes Chromosomes Cancer. 1994 Dec; 11(4):216-21.
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Multicolor FISH mapping of YAC clones in 3p14 and identification of a YAC spanning both FRA3B and the t(3;8) associated with hereditary renal cell carcinoma. Genomics. 1994 Jul 15; 22(2):319-26.
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Enhanced G2 chromatid radiosensitivity in dyskeratosis congenita fibroblasts. Am J Hum Genet. 1990 Feb; 46(2):350-7.
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Loss of common 3p14 fragile site expression in renal cell carcinoma with deletion breakpoint at 3p14. Cancer Genet Cytogenet. 1988 Mar; 31(1):75-82.
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Translocation t(3;8)(p14.2;q24.1) in renal cell carcinoma affects expression of the common fragile site at 3p14(FRA3B) in lymphocytes. Cancer Genet Cytogenet. 1988 Mar; 31(1):69-73.
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DNA demethylation induced by 5-azacytidine does not affect fragile X expression. Am J Hum Genet. 1986 Mar; 38(3):309-18.