"Chromosomal Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.
| Descriptor ID |
D043171
|
| MeSH Number(s) |
C23.550.210.110 C23.550.362.180 G05.365.590.175.165 G05.370.180
|
| Concept/Terms |
Chromosomal Instability- Chromosomal Instability
- Chromosomal Instabilities
- Instabilities, Chromosomal
- Instability, Chromosomal
- Chromosome Instability
- Chromosome Instabilities
- Instabilities, Chromosome
- Instability, Chromosome
Chromosome Stability- Chromosome Stability
- Chromosome Stabilities
- Stabilities, Chromosome
- Stability, Chromosome
- Chromosomal Stability
- Chromosomal Stabilities
- Stabilities, Chromosomal
- Stability, Chromosomal
|
Below are MeSH descriptors whose meaning is more general than "Chromosomal Instability".
Below are MeSH descriptors whose meaning is more specific than "Chromosomal Instability".
This graph shows the total number of publications written about "Chromosomal Instability" by people in this website by year, and whether "Chromosomal Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Chromosomal Instability" by people in Profiles.
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Polysomy is associated with poor outcome in 1p/19q codeleted oligodendroglial tumors. Neuro Oncol. 2019 09 06; 21(9):1164-1174.
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The broken cycle: E2F dysfunction in?cancer. Nat Rev Cancer. 2019 06; 19(6):326-338.
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Thiopurine-induced mitotic catastrophe in Rad51d-deficient mammalian cells. Environ Mol Mutagen. 2018 01; 59(1):38-48.
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PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27. Mol Cancer Res. 2016 07; 14(7):634-46.
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The homologous recombination protein RAD51D mediates the processing of 6-thioguanine lesions downstream of mismatch repair. Mol Cancer Res. 2011 Feb; 9(2):206-14.
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The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion. Nucleic Acids Res. 2011 Jan; 39(1):132-45.
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Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nat Genet. 2009 May; 41(5):518-20.
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Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. JAMA. 2005 Apr 27; 293(16):1979-85.
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Extensive chromosomal instability in Rad51d-deficient mouse cells. Cancer Res. 2005 Mar 15; 65(6):2089-96.
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Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells. Breast Cancer Res. 2004; 6(5):R531-9.