"Microglia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
| Descriptor ID |
D017628
|
| MeSH Number(s) |
A08.637.400 A11.650.400
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microglia".
Below are MeSH descriptors whose meaning is more specific than "Microglia".
This graph shows the total number of publications written about "Microglia" by people in this website by year, and whether "Microglia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 1 | 3 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 3 | 3 | 6 |
| 2005 | 0 | 4 | 4 |
| 2006 | 3 | 1 | 4 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 3 | 4 |
| 2010 | 3 | 0 | 3 |
| 2011 | 1 | 5 | 6 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 4 | 3 | 7 |
| 2015 | 0 | 7 | 7 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 5 | 5 |
| 2019 | 6 | 3 | 9 |
| 2020 | 5 | 2 | 7 |
| 2021 | 1 | 3 | 4 |
| 2022 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Microglia" by people in Profiles.
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Site-Specific knockdown of microglia in the locus coeruleus regulates hypervigilant responses to social stress in female rats. Brain Behav Immun. 2023 03; 109:190-203.
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p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia. Mol Neurobiol. 2022 Sep; 59(9):5284-5298.
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BAY 11-7082 inhibits the secretion of interleukin-6 by senescent human microglia. Biochem Biophys Res Commun. 2022 08 20; 617(Pt 1):30-35.
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Protective Effects of Estrogen via Nanoparticle Delivery to Attenuate Myelin Loss and Neuronal Death after Spinal Cord Injury. Neurochem Res. 2021 Nov; 46(11):2979-2990.
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Interactions of neuroimmune signaling and glutamate plasticity in addiction. J Neuroinflammation. 2021 Feb 21; 18(1):56.
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Delayed Administration of Angiotensin Receptor (AT2R) Agonist C21 Improves Survival and Preserves Sensorimotor Outcomes in Female Diabetic Rats Post-Stroke through Modulation of Microglial Activation. Int J Mol Sci. 2021 Jan 29; 22(3).
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Complement Drives Synaptic Degeneration and Progressive Cognitive Decline in the Chronic Phase after Traumatic Brain Injury. J Neurosci. 2021 02 24; 41(8):1830-1843.
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Neuroinflammatory responses of microglia in central nervous system trauma. J Cereb Blood Flow Metab. 2020 12; 40(1_suppl):S25-S33.
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Diabetic rats are more susceptible to cognitive decline in a model of microemboli-mediated vascular contributions to cognitive impairment and dementia. Brain Res. 2020 12 15; 1749:147132.
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Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System. Front Immunol. 2020; 11:566892.