| Item Type | Name |
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Academic Article
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Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages.
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Academic Article
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Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
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Academic Article
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Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy.
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Academic Article
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Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy.
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Academic Article
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N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes.
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Academic Article
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Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
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Academic Article
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Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells.
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Academic Article
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Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages.
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Academic Article
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Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy.
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Academic Article
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Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy.
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Academic Article
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Rhinovirus-induced oxidative stress and interleukin-8 elaboration involves p47-phox but is independent of attachment to intercellular adhesion molecule-1 and viral replication.
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Academic Article
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The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells.
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Academic Article
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Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide.
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Academic Article
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Effect of rhinovirus challenge on antioxidant enzymes in respiratory epithelial cells.
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Academic Article
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Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy.
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Academic Article
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
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Academic Article
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A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
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Academic Article
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N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain.
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Academic Article
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Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability.
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Academic Article
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Endotoxin induces structure-function alterations of rat liver peroxisomes: Kupffer cells released factors as possible modulators.
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Academic Article
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Isolation and biochemical characterization of peroxisomes from cultured rat glial cells.
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Academic Article
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Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.
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Academic Article
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A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma.
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Academic Article
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Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells.
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Academic Article
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5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.
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Academic Article
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HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
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Academic Article
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Rho/ROCK pathway as a target of tumor therapy.
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Academic Article
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Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death.
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Academic Article
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T-bet is essential for the progression of experimental autoimmune encephalomyelitis.
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Academic Article
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Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
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Academic Article
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Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury.
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Academic Article
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Rhizomelic chondrodysplasia punctata: biochemical studies of peroxisomes isolated from cultured skin fibroblasts.
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Academic Article
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S-nitrosoglutathione prevents interphotoreceptor retinoid-binding protein (IRBP(161-180))-induced experimental autoimmune uveitis.
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Academic Article
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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
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Academic Article
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Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
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Academic Article
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Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis.
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Academic Article
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Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.
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Academic Article
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Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy.
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Academic Article
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Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.
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Academic Article
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The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke.
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Academic Article
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Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes.
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Academic Article
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Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-a-dependent mechanism.
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Academic Article
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The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein.
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Academic Article
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The human palmitoyl-CoA ligase (FACL2) gene maps to the chromosome 4q34-q35 region by fluorescence in situ hybridization (FISH) and somatic cell hybrid panels.
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Academic Article
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Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes.
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Academic Article
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Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz.
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Academic Article
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Phytanic acid alpha-oxidation in human cultured skin fibroblasts.
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Academic Article
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Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes.
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Academic Article
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The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase.
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Academic Article
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Biochemical features of a patient with Zellweger-like syndrome with normal PTS-1 and PTS-2 peroxisomal protein import systems: a new peroxisomal disease.
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Academic Article
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Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E.
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Academic Article
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The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma.
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Academic Article
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S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke.
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Academic Article
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Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction.
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Academic Article
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IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases.
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Academic Article
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction.
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Academic Article
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Immunomodulatory effects of 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors, potential therapy for relapsing remitting multiple sclerosis.
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Academic Article
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Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats.
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Academic Article
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GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions.
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Academic Article
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Modulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures.
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Academic Article
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Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.
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Academic Article
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The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease.
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Academic Article
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Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.
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Academic Article
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Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine.
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Academic Article
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Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin.
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Academic Article
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Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.
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Academic Article
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Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts.
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Academic Article
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S-nitrosoglutathione a physiologic nitric oxide carrier attenuates experimental autoimmune encephalomyelitis.
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Academic Article
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Activation of PPAR-? and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
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Academic Article
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Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis.
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Academic Article
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In situ genetic complementation analysis of cells with generalized peroxisomal dysfunction.
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Academic Article
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Synergistic activity of interleukin-17 and tumor necrosis factor-a enhances oxidative stress-mediated oligodendrocyte apoptosis.
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Academic Article
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Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion.
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Academic Article
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S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions.
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Academic Article
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Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells.
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Academic Article
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The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein.
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Academic Article
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Visualization of multiple imidazoline/guanidinium-receptive sites.
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Academic Article
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Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts.
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Academic Article
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Phytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata.
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Academic Article
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Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis.
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Academic Article
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Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes.
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Academic Article
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Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells.
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Concept
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Epithelial Cells
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Concept
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Hybrid Cells
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Concept
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PC12 Cells
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Concept
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Kupffer Cells
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Concept
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Endothelial Cells
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Concept
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CHO Cells
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Concept
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T-Lymphocytes, Regulatory
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Concept
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Leukemia-Lymphoma, Adult T-Cell
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Concept
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T-Lymphocyte Subsets
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Concept
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Tumor Cells, Cultured
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Concept
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Epitopes, T-Lymphocyte
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Concept
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Cells, Cultured
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Concept
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Stem Cells
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Concept
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T-Lymphocytes
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Concept
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Lymphocytes
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Concept
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Th1 Cells
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Concept
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Induced Pluripotent Stem Cells
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Concept
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Photoreceptor Cells
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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Th2 Cells
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Concept
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B-Lymphocytes
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Concept
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Myeloid Cells
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Academic Article
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Berry anthocyanidins synergistically suppress growth and invasive potential of human non-small-cell lung cancer cells.
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Academic Article
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STAT3 regulation by S-nitrosylation: implication for inflammatory disease.
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Academic Article
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Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease.
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Academic Article
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ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy.
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Academic Article
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Role of S-nitrosoglutathione mediated mechanisms in tau hyper-phosphorylation.
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Academic Article
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AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis.
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Academic Article
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Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy.
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Academic Article
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S-Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide-induced sepsis.
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Academic Article
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MicroRNA Profiling Identifies miR-196a as Differentially Expressed in Childhood Adrenoleukodystrophy and Adult Adrenomyeloneuropathy.
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Academic Article
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Combinatorial Effect of Metformin and Lovastatin Impedes T-cell Autoimmunity and Neurodegeneration in Experimental Autoimmune Encephalomyelitis.
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Academic Article
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GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1a.
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Academic Article
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S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis.
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Academic Article
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Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione.
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Academic Article
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Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries.
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Academic Article
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Hypoxia-inducible factor-1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases.
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Concept
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Neural Stem Cells
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Concept
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Th17 Cells
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Academic Article
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Regulation of B cell functions by S-nitrosoglutathione in the EAE model.
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Academic Article
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Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis.
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