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Rohrer, Baerbel
One or more keywords matched the following properties of Rohrer, Baerbel
PropertyValue
keywords Retinal Degenerative Diseases
preferred title Endowed Chair, Gene & Pharmaceutical Treatment of Retinal Degenerative Disease
One or more keywords matched the following items that are connected to Rohrer, Baerbel
Item TypeName
Academic Article Gene dosage effect of the TrkB receptor on rod physiology and biochemistry in juvenile mouse retina.
Academic Article Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging.
Academic Article Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice.
Academic Article Functionally intact glutamate-mediated signaling in bipolar cells of the TRKB knockout mouse retina.
Academic Article Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages.
Academic Article 9-cis Retinal increased in retina of RPE65 knockout mice with decrease in coat pigmentation.
Academic Article Rod and cone pigment regeneration in RPE65-/- mice.
Academic Article Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage.
Academic Article Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.
Academic Article Synthesis, pharmacokinetics, efficacy, and rat retinal toxicity of a novel mitomycin C-triamcinolone acetonide conjugate.
Academic Article A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
Academic Article Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement.
Academic Article A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Academic Article The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization.
Academic Article Differential effects of rapamycin on rods and cones during light-induced stress in albino mice.
Academic Article 11-cis-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors.
Academic Article Early alterations in mitochondrial reserve capacity; a means to predict subsequent photoreceptor cell death.
Academic Article Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.
Academic Article Structure-function analysis of rods and cones in juvenile, adult, and aged C57bl/6 and Balb/c mice.
Academic Article Does constitutive phosphorylation protect against photoreceptor degeneration in Rpe65-/- mice?
Academic Article Multidestructive pathways triggered in photoreceptor cell death of the rd mouse as determined through gene expression profiling.
Academic Article Identification of RDH10, an All-trans Retinol Dehydrogenase, in Retinal Muller Cells.
Academic Article Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.
Academic Article Long-term ERG analysis in the partially light-damaged mouse retina reveals regressive and compensatory changes.
Academic Article Classical complement activation and acquired immune response pathways are not essential for retinal degeneration in the rd1 mouse.
Academic Article Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.
Academic Article Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism.
Academic Article Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis.
Academic Article Explant cultures of Rpe65-/- mouse retina: a model to investigate cone opsin trafficking.
Concept Retinal Pigment Epithelium
Concept Retinal Ganglion Cells
Concept Retinal Neovascularization
Concept Retinal Pigments
Concept Retinaldehyde
Concept Retinal Degeneration
Concept Retinal Rod Photoreceptor Cells
Concept Retinal Diseases
Concept Retinal Cone Photoreceptor Cells
Academic Article Prolonged SRC kinase activation, a mechanism to turn transient, sublytic complement activation into a sustained pathological condition in retinal pigment epithelium cells.
Academic Article Autophagy is one of the multiple mechanisms active in photoreceptor degeneration.
Academic Article Apoptosis and autophagy in photoreceptors exposed to oxidative stress.
Academic Article Paradoxical role of BDNF: BDNF+/- retinas are protected against light damage-mediated stress.
Academic Article Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers.
Academic Article Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells.
Academic Article Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation.
Academic Article A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury.
Academic Article Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and ?dT-cells.
Academic Article Reduced Metabolic Capacity in Aged Primary Retinal Pigment Epithelium (RPE) is Correlated with Increased Susceptibility to Oxidative Stress.
Academic Article Small Molecules that Protect Mitochondrial Function from Metabolic Stress Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models.
Academic Article Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization.
Academic Article Activation of endogenously expressed ion channels by active complement in the retinal pigment epithelium.
Academic Article Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis.
Academic Article Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement.
Academic Article Photoreceptor structure and function is maintained in organotypic cultures of mouse retinas.
Academic Article Identification of candidate genes for human retinal degeneration loci using differentially expressed genes from mouse photoreceptor dystrophy models.
Academic Article Sustained elevation of intracellular cGMP causes oxidative stress triggering calpain-mediated apoptosis in photoreceptor degeneration.
Academic Article Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death.
Academic Article Anaphylatoxin Signaling in Retinal Pigment and Choroidal Endothelial Cells: Characteristics and Relevance to Age-Related Macular Degeneration.
Academic Article Recombinant Manganese Peroxidase Reduces A2E Burden in Age-Related and Stargardt's Macular Degeneration Models.
Academic Article Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System.
Academic Article Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.
Academic Article Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury.
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  • Retinaldehyde