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Leone, Gustavo
One or more keywords matched the following items that are connected to Leone, Gustavo
Item TypeName
Concept Mice, Knockout
Concept Mice, Inbred C3H
Concept Mice
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Concept Mice, Inbred NOD
Concept Mice, Nude
Concept Mice, SCID
Concept Mice, Inbred Strains
Concept Mice, Inbred NZB
Concept Mice, Mutant Strains
Academic Article Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.
Academic Article Structural characterization of Rasgrf1 and a novel linked imprinted locus.
Academic Article Extra-embryonic function of Rb is essential for embryonic development and viability.
Academic Article Inactivation of E2F3 results in centrosome amplification.
Academic Article Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice.
Academic Article Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation.
Academic Article Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells.
Academic Article Aberrant regulation of survivin by the RB/E2F family of proteins.
Academic Article A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies.
Academic Article Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.
Academic Article Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice.
Academic Article E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7.
Academic Article Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.
Academic Article Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.
Academic Article E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.
Academic Article Rb is critical in a mammalian tissue stem cell population.
Academic Article Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.
Academic Article Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.
Academic Article Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.
Academic Article Detection and visualization of surface-pockets to enable phenotyping studies.
Academic Article CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.
Academic Article Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
Academic Article Direct evidence for epithelial-mesenchymal transitions in breast cancer.
Academic Article Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.
Academic Article An imaging workflow for characterizing phenotypical change in large histological mouse model datasets.
Academic Article Mouse development with a single E2F activator.
Academic Article Tensor classification of N-point correlation function features for histology tissue segmentation.
Academic Article E2f3a and E2f3b contribute to the control of cell proliferation and mouse development.
Academic Article Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.
Academic Article Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Academic Article Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.
Academic Article E2F3 is a mediator of DNA damage-induced apoptosis.
Academic Article Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.
Academic Article Division and apoptosis of E2f-deficient retinal progenitors.
Academic Article E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Academic Article An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
Academic Article Allele-specific tumor spectrum in pten knockin mice.
Academic Article E2f1-3 are critical for myeloid development.
Academic Article Cell proliferation in the absence of E2F1-3.
Academic Article Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution.
Academic Article S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.
Academic Article Atypical E2F repressors and activators coordinate placental development.
Academic Article E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1.
Academic Article Canonical and atypical E2Fs regulate the mammalian endocycle.
Academic Article Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells.
Academic Article Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Academic Article PTEN is a negative regulator of NK cell cytolytic function.
Academic Article Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Academic Article Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Academic Article The Spectrum of E2F in Liver Disease--Mediated Regulation in Biology and Cancer.
Academic Article FGFR and PTEN signaling interact during lens development to regulate cell survival.
Academic Article Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice.
Academic Article E2f8 mediates tumor suppression in postnatal liver development.
Academic Article Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Academic Article Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
Academic Article Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Academic Article Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Academic Article The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.
Academic Article Loss of fibroblast HIF-1a accelerates tumorigenesis.
Academic Article Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
Academic Article E2f3 in tumor macrophages promotes lung metastasis.
Academic Article Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps.
Academic Article CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Academic Article NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development.
Academic Article Stromal PTEN determines mammary epithelial response to radiotherapy.
Academic Article Endoreduplication of the mouse genome in the absence of ORC1.
Academic Article hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
Academic Article Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Academic Article Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
Academic Article Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Academic Article Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis.
Academic Article A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.
Academic Article The E2F1-3 transcription factors are essential for cellular proliferation.
Academic Article Myc requires distinct E2F activities to induce S phase and apoptosis.
Academic Article Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
Academic Article RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
Academic Article annoPeak: a web application to annotate and visualize peaks from ChIP-seq/ChIP-exo-seq.
Academic Article Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
Academic Article Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression.
Academic Article DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2.
Academic Article Rb regulates proliferation and rod photoreceptor development in the mouse retina.
Academic Article Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages.
Academic Article Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta.
Academic Article Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2.
Academic Article Identifying nuclear phenotypes using semi-supervised metric learning.
Academic Article Non-parametric population analysis of cellular phenotypes.
Academic Article The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway.
Academic Article A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.
Academic Article Cited2 is required in trophoblasts for correct placental capillary patterning.
Academic Article Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation.
Academic Article Crosstalk between PKCa and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium.
Academic Article Periostin/?1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization.
Academic Article Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.
Academic Article Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
Academic Article Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function.
Academic Article The N-terminal quarter of reovirus cell attachment protein sigma 1 possesses intrinsic virion-anchoring function.
Academic Article Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment.
Academic Article The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.
Academic Article Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells.
Academic Article Tissue-specific targeting of cell fate regulatory genes by E2f factors.
Academic Article Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.
Academic Article Abrupt involution induces inflammation, estrogenic signaling, and hyperplasia linking lack of breastfeeding with increased risk of breast cancer.
Academic Article Modeling Human Cancer-induced Cachexia.
Academic Article Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.
Academic Article BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
Academic Article Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma.
Academic Article Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta.
Academic Article Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain.
Academic Article Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia.
Concept Mice, 129 Strain
Academic Article Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.
Academic Article RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Academic Article Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss.
Academic Article Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human.
Academic Article STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Academic Article Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images.
Academic Article Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
Academic Article The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
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