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    • E2f8 mediates tumor suppression in postnatal liver development.
    • Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration-resistant prostate cancer.
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E2f8 mediates tumor suppression in postnatal liver development.

E2f8 mediates tumor suppression in postnatal liver development. J Clin Invest. 2016 08 01; 126(8):2955-69.

View in: PubMed

subject areas
  • Alleles
  • Animals
  • Biopsy
  • Carcinoma, Hepatocellular
  • Cell Proliferation
  • Cell Survival
  • DNA
  • E2F7 Transcription Factor
  • Female
  • Gene Deletion
  • Genotype
  • Hepatocytes
  • Humans
  • Liver
  • Liver Neoplasms
  • Male
  • Mice
  • Oligonucleotide Array Sequence Analysis
  • Protein Binding
  • Protein Domains
  • Repressor Proteins
  • Sequence Analysis, RNA
  • Signal Transduction

authors with profiles
  • Lindsey Kent
  • Maria Cuitino
  • Gustavo Leone
  • Christopher S Koivisto