Perry V. Halushka, M.D., Ph.D. is a Distinguished University Professor of Cell and Molecular Pharmacology, the Program Director of Medical Scientist Training Program, and dean emeritus of the College of Graduate Studies. He received his Ph.D. degree in 1967 and M.D. degree in 1970 from the University of Chicago. After internship and residency in Internal Medicine at Grady Memorial Hospital, he spent two years at the NIH, Experimental Therapeutics Branch. In 1974, he joined the faculty of the Medical University of South Carolina.
Dr. Halushka¹s research has revolved around molecular characterizations and regulation of Thromboxane A2 receptors in health and disease. "The long term objective of our research program is to determine the role of thromboxane A2 receptors in disease processes with a particular emphasis in cancer. In collaboration with Drs. Omar Moussa and Dennis Watson we have found that there is an over-expression of the beta isoform of thromboxane A2 receptors in bladder cancer tissue and cell lines. The over-expression is associated with a poorer prognosis in patients with bladder cancer. Current studies are focused on determining the mechanisms for: 1) the over-expression of the receptors and 2) the signaling pathways involved in the oncogenic effects. The observations made in these studies may have wider applicability to other cancers."