"Pancreatic Elastase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.
| Descriptor ID |
D010196
|
| MeSH Number(s) |
D08.811.277.656.300.760.560 D08.811.277.656.959.350.560
|
| Concept/Terms |
Pancreatic Elastase- Pancreatic Elastase
- Elastase, Pancreatic
- Pancreatic Elastase I
- Elastase I, Pancreatic
- Elastase
- Pancreatopeptidase
|
Below are MeSH descriptors whose meaning is more general than "Pancreatic Elastase".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Elastase".
This graph shows the total number of publications written about "Pancreatic Elastase" by people in this website by year, and whether "Pancreatic Elastase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Pancreatic Elastase" by people in Profiles.
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Dhital S, Rice CD, Vyavahare NR. Reversal of elastase-induced abdominal aortic aneurysm following the delivery of nanoparticle-based pentagalloyl glucose (PGG) is associated with reduced inflammatory and immune markers. Eur J Pharmacol. 2021 Nov 05; 910:174487.
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Lane BA, Chakrabarti M, Ferruzzi J, Azhar M, Eberth JF. Mechanics of ascending aortas from TGFß-1, -2, -3 haploinsufficient mice and elastase-induced aortopathy. J Biomech. 2021 08 26; 125:110543.
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Lane BA, Wang X, Lessner SM, Vyavahare NR, Eberth JF. Targeted Gold Nanoparticles as an Indicator of Mechanical Damage in an Elastase Model of Aortic Aneurysm. Ann Biomed Eng. 2020 Aug; 48(8):2268-2278.
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Dhital S, Vyavahare NR. Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice. PLoS One. 2020; 15(3):e0227165.
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Vanga RR, Tansel A, Sidiq S, El-Serag HB, Othman MO. Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2018 08; 16(8):1220-1228.e4.
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Tian Y, Zhang W, Sun J, Zhai H, Yu Y, Qi X, Jones JA, Zhong H. A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase. J Vasc Surg. 2018 01; 67(1):300-308.e2.
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Munjal C, Jegga AG, Opoka AM, Stoilov I, Norris RA, Thomas CJ, Smith JM, Mecham RP, Bressan GM, Hinton RB. Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model. Physiol Rep. 2017 Mar; 5(5).
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Tam H, Zhang W, Feaver KR, Parchment N, Sacks MS, Vyavahare N. A novel crosslinking method for improved tear resistance and biocompatibility of tissue based biomaterials. Biomaterials. 2015 Oct; 66:83-91.
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Li H, Su M, Hamann MT, Bowling JJ, Kim HS, Jung JH. Solution structure of a sponge-derived cystine knot peptide and its notable stability. J Nat Prod. 2014 Feb 28; 77(2):304-10.
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Gacchina CE, Deb P, Barth JL, Ramamurthi A. Elastogenic inductability of smooth muscle cells from a rat model of late stage abdominal aortic aneurysms. Tissue Eng Part A. 2011 Jul; 17(13-14):1699-711.