"Factor XIa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium.
| Descriptor ID |
D015945
|
| MeSH Number(s) |
D08.811.277.656.300.760.320 D08.811.277.656.959.350.320 D12.776.124.125.425.320 D23.119.425.320
|
| Concept/Terms |
Factor XIa- Factor XIa
- Factor Eleven A
- Activated Factor XI
- Coagulation Factor XIa
- Factor XIa, Coagulation
- Blood Coagulation Factor XI, Activated
- Contact Activation Product
- Factor 11A
- Factor XI, Activated
|
Below are MeSH descriptors whose meaning is more general than "Factor XIa".
Below are MeSH descriptors whose meaning is more specific than "Factor XIa".
This graph shows the total number of publications written about "Factor XIa" by people in this website by year, and whether "Factor XIa" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor XIa" by people in Profiles.
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The complement and contact activation systems: partnership in pathogenesis beyond angioedema. Immunol Rev. 2016 11; 274(1):281-289.
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Kinins, airway obstruction, and anaphylaxis. Chem Immunol Allergy. 2010; 95:67-84.
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Activation of factor XI in plasma is dependent on factor XII. Blood. 1993 Feb 01; 81(3):580-6.