"Furin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage near paired ARGININE residues that are separated by two amino acids.
| Descriptor ID |
D045683
|
| MeSH Number(s) |
D08.811.277.656.300.760.353 D08.811.277.656.837.249 D08.811.277.656.959.350.353
|
| Concept/Terms |
Furin- Furin
- Dibasic Processing Enzyme
- Processing Enzyme, Dibasic
- Furin Protein
- SPC1 Proteinase
- Paired Basic Amino Acid Cleaving Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Furin".
Below are MeSH descriptors whose meaning is more specific than "Furin".
This graph shows the total number of publications written about "Furin" by people in this website by year, and whether "Furin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Furin" by people in Profiles.
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Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy. Cell Chem Biol. 2022 06 16; 29(6):927-929.
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miR-133a Replacement Attenuates Thoracic Aortic Aneurysm in Mice. J Am Heart Assoc. 2021 08 17; 10(16):e019862.
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Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway. Mol Cell Biol. 2007 Apr; 27(8):2997-3007.