"Second Messenger Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.
| Descriptor ID |
D015290
|
| MeSH Number(s) |
G02.111.820.800 G04.835.800
|
| Concept/Terms |
Second Messenger Systems- Second Messenger Systems
- Second Messenger System
- System, Second Messenger
- Systems, Second Messenger
- Intracellular Second Messengers
- Intracellular Second Messenger
- Messengers, Intracellular Second
- Second Messenger, Intracellular
- Second Messengers, Intracellular
Second Messengers- Second Messengers
- Messenger, Second
- Messengers, Second
- Second Messenger
|
Below are MeSH descriptors whose meaning is more general than "Second Messenger Systems".
Below are MeSH descriptors whose meaning is more specific than "Second Messenger Systems".
This graph shows the total number of publications written about "Second Messenger Systems" by people in this website by year, and whether "Second Messenger Systems" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 1 | 2 |
| 1995 | 3 | 3 | 6 |
| 1996 | 1 | 2 | 3 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Second Messenger Systems" by people in Profiles.
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Gibbs WS, Garrett SM, Beeson CC, Schnellmann RG. Identification of dual mechanisms mediating 5-hydroxytryptamine receptor 1F-induced mitochondrial biogenesis. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F260-F268.
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Bobay BG, Thompson RJ, Hoch JA, Cavanagh J. Long range dynamic effects of point-mutations trap a response regulator in an active conformation. FEBS Lett. 2010 Oct 08; 584(19):4203-7.
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Villa NY, Kupchak BR, Garitaonandia I, Smith JL, Alonso E, Alford C, Cowart LA, Hannun YA, Lyons TJ. Sphingolipids function as downstream effectors of a fungal PAQR. Mol Pharmacol. 2009 Apr; 75(4):866-75.
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Jin J, Hou Q, Mullen TD, Zeidan YH, Bielawski J, Kraveka JM, Bielawska A, Obeid LM, Hannun YA, Hsu YT. Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. J Biol Chem. 2008 Sep 26; 283(39):26509-17.
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Won JS, Singh AK, Singh I. Lactosylceramide: a lipid second messenger in neuroinflammatory disease. J Neurochem. 2007 Nov; 103 Suppl 1:180-91.
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Zapata A, Kivell B, Han Y, Javitch JA, Bolan EA, Kuraguntla D, Jaligam V, Oz M, Jayanthi LD, Samuvel DJ, Ramamoorthy S, Shippenberg TS. Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. J Biol Chem. 2007 Dec 07; 282(49):35842-54.
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Yu J, Novgorodov SA, Chudakova D, Zhu H, Bielawska A, Bielawski J, Obeid LM, Kindy MS, Gudz TI. JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction. J Biol Chem. 2007 Aug 31; 282(35):25940-9.
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Lapierre LA, Avant KM, Caldwell CM, Ham AJ, Hill S, Williams JA, Smolka AJ, Goldenring JR. Characterization of immunoisolated human gastric parietal cells tubulovesicles: identification of regulators of apical recycling. Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5):G1249-62.
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Wu Q, Chen C, Koutalos Y. Longitudinal diffusion of a polar tracer in the outer segments of rod photoreceptors from different species. Photochem Photobiol. 2006 Nov-Dec; 82(6):1447-51.
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Marchesini N, Hannun YA. Acid and neutral sphingomyelinases: roles and mechanisms of regulation. Biochem Cell Biol. 2004 Feb; 82(1):27-44.