"Genes, abl" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
| Descriptor ID |
D016313
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.100
|
| Concept/Terms |
bcr-v-abl Oncogenes- bcr-v-abl Oncogenes
- Oncogene, bcr-v-abl
- Oncogenes, bcr-v-abl
- bcr v abl Oncogenes
- bcr-v-abl Oncogene
abl Oncogene- abl Oncogene
- Oncogene, abl
- Oncogenes, abl
- abl Oncogenes
- v-abl Oncogenes
- Oncogene, v-abl
- Oncogenes, v-abl
- v abl Oncogenes
- v-abl Oncogene
- v-abl Genes
- Gene, v-abl
- Genes, v-abl
- v abl Genes
- v-abl Gene
bcr-abl Proto-Oncogenes- bcr-abl Proto-Oncogenes
- Proto-Oncogene, bcr-abl
- Proto-Oncogenes, bcr-abl
- bcr abl Proto Oncogenes
- bcr-abl Proto-Oncogene
c-abl Genes- c-abl Genes
- Gene, c-abl
- Genes, c-abl
- c abl Genes
- c-abl Gene
- c-abl Proto-Oncogenes
- Proto-Oncogene, c-abl
- Proto-Oncogenes, c-abl
- c abl Proto Oncogenes
- c-abl Proto-Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Genes, abl".
Below are MeSH descriptors whose meaning is more specific than "Genes, abl".
This graph shows the total number of publications written about "Genes, abl" by people in this website by year, and whether "Genes, abl" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, abl" by people in Profiles.
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Sphingomyelin synthase 1 activity is regulated by the BCR-ABL oncogene. J Lipid Res. 2013 Mar; 54(3):794-805.
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Quantitative measurement of BCR/abl transcripts using real-time polymerase chain reaction. Ann Oncol. 2002 May; 13(5):781-8.
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Biologically-based risk estimation for radiation-induced chronic myeloid leukemia. Radiat Environ Biophys. 2000 Sep; 39(3):153-9.
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Sodium vanadate, a tyrosine phosphatase inhibitor, affects expression of hematopoietic growth factors and extracellular matrix RNAs in SV40-transformed human marrow stromal cells. Exp Hematol. 1992 May; 20(4):449-53.