Factor VIIa

"Factor VIIa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.

Descriptor ID	D015942
MeSH Number(s)	D08.811.277.656.300.760.300 D08.811.277.656.959.350.300 D12.776.124.125.325.300 D23.119.325.300
Concept/Terms	Factor VIIa Factor VIIa Coagulation Factor VIIa Factor VIIa, Coagulation Blood Coagulation Factor VII, Activated Factor VII, Activated Activated Factor VII Factor 7A Factor Seven A

Below are MeSH descriptors whose meaning is more general than "Factor VIIa".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Serine Endopeptidases [D08.811.277.656.300.760]
Factor VIIa [D08.811.277.656.300.760.300]
Serine Proteases [D08.811.277.656.959]
Serine Endopeptidases [D08.811.277.656.959.350]
Factor VIIa [D08.811.277.656.959.350.300]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
Factor VII [D12.776.124.125.325]
Factor VIIa [D12.776.124.125.325.300]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Factor VII [D23.119.325]
Factor VIIa [D23.119.325.300]

Below are MeSH descriptors whose meaning is more specific than "Factor VIIa".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Factor VIIa" by people in this website by year, and whether "Factor VIIa" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 4 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2007	0	1	1
2008	1	0	1
2011	3	1	4
2012	0	1	1
2013	1	0	1
2014	1	0	1
2019	1	0	1
2021	0	1	1

Below are the most recent publications written about "Factor VIIa" by people in Profiles.

Naidech AM, Grotta J, Elm J, Janis S, Dowlatshahi D, Toyoda K, Steiner T, Mayer SA, Khanolkar P, Denlinger J, Audebert HJ, Molina C, Khatri P, Sprigg N, Vagal A, Broderick JP. Recombinant factor VIIa for hemorrhagic stroke treatment at earliest possible time (FASTEST): Protocol for a phase III, double-blind, randomized, placebo-controlled trial. Int J Stroke. 2022 Aug; 17(7):806-809.

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Gladstone DJ, Aviv RI, Demchuk AM, Hill MD, Thorpe KE, Khoury JC, Sucharew HJ, Al-Ajlan F, Butcher K, Dowlatshahi D, Gubitz G, De Masi S, Hall J, Gregg D, Mamdani M, Shamy M, Swartz RH, Del Campo CM, Cucchiara B, Panagos P, Goldstein JN, Carrozzella J, Jauch EC, Broderick JP, Flaherty ML. Effect of Recombinant Activated Coagulation Factor VII on Hemorrhage Expansion Among Patients With Spot Sign-Positive Acute Intracerebral Hemorrhage: The SPOTLIGHT and STOP-IT Randomized Clinical Trials. JAMA Neurol. 2019 12 01; 76(12):1493-1501.

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Connors NJ, Gill J, Nakanishi A, Hoffman RS. Porcine blood and surrogate markers do not prove benefit of aDabi-Fab. Crit Care. 2014 Jun 17; 18(3):435.

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Scheffert JL, Taber DJ, Pilch NA, McGillicuddy JW, Baliga PK, Chavin KD. Timing of factor VIIa in liver transplantation impacts cost and clinical outcomes. Pharmacotherapy. 2013 May; 33(5):483-8.

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Menkis AH, Martin J, Cheng DC, Fitzgerald DC, Freedman JJ, Gao C, Koster A, Mackenzie GS, Murphy GJ, Spiess B, Ad N. Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011. Innovations (Phila). 2012 Jul-Aug; 7(4):229-41.

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Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, Uber WE, Reeves ST, McGowan FX, Bradley SM, Spinale FG. Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2012 May; 143(5):1069-76.

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Meadows HB, Krisl JC, Greenberg CS, Mazur JE. The use of activated recombinant factor VII in a patient with fulminant hepatic failure requiring placement of an intracranial pressure monitor. Ann Pharmacother. 2011 Nov; 45(11):e60.

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Krisl JC, Meadows HE, Greenberg CS, Mazur JE. Clinical usefulness of recombinant activated factor VII in patients with liver failure undergoing invasive procedures. Ann Pharmacother. 2011 Nov; 45(11):1433-8.

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Uber WE, Toole JM, Stroud MR, Haney JS, Lazarchick J, Crawford FA, Ikonomidis JS. Administration of recombinant activated factor VII in the intensive care unit after complex cardiovascular surgery: clinical and economic outcomes. J Thorac Cardiovasc Surg. 2011 Jun; 141(6):1469-77.e2.

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Bowman LJ, Uber WE, Stroud MR, Christiansen LR, Lazarchick J, Crumbley AJ, Kratz JM, Toole JM, Crawford FA, Ikonomidis JS. Use of recombinant activated factor VII concentrate to control postoperative hemorrhage in complex cardiovascular surgery. Ann Thorac Surg. 2008 May; 85(5):1669-76; discussion 1676-7.

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