beta 2-Glycoprotein I

"beta 2-Glycoprotein I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.

Descriptor ID	D053482
MeSH Number(s)	D12.776.124.117 D12.776.395.195
Concept/Terms	beta 2-Glycoprotein I beta 2-Glycoprotein I beta 2 Glycoprotein I Apo H Endothelial Cell-Viability Maintaining Factor Endothelial Cell Viability Maintaining Factor beta(2)GPI beta2-Glycoprotein I beta2 Glycoprotein I EC-VMFa EC VMFa Anticardiolipin Cofactor Cofactor, Anticardiolipin Apolipoprotein H

Below are MeSH descriptors whose meaning is more general than "beta 2-Glycoprotein I".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
beta 2-Glycoprotein I [D12.776.124.117]
Glycoproteins [D12.776.395]
beta 2-Glycoprotein I [D12.776.395.195]

Below are MeSH descriptors whose meaning is related to "beta 2-Glycoprotein I".

Below are MeSH descriptors whose meaning is more specific than "beta 2-Glycoprotein I".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "beta 2-Glycoprotein I" by people in this website by year, and whether "beta 2-Glycoprotein I" was a major or minor topic of these publications.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2009	0	1	1
2013	1	0	1
2019	0	2	2
2020	1	0	1
2021	0	1	1

Below are the most recent publications written about "beta 2-Glycoprotein I" by people in Profiles.

Elkhalifa M, Orbai AM, Magder LS, Petri M, Alarcón GS, Gordon C, Merrill J, Fortin PR, Bruce IN, Isenberg D, Wallace D, Nived O, Ramsey-Goldman R, Bae SC, Hanly JG, Sanchez-Guerrero J, Clarke AE, Aranow C, Manzi S, Urowitz M, Gladman DD, Kalunian K, Werth VP, Zoma A, Bernatsky S, Khamashta M, Jacobsen S, Buyon JP, Dooley MA, Vollenhoven RV, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim S, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG. Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset. Lupus. 2021 Jul; 30(8):1283-1288.

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Hollerbach A, Müller-Calleja N, Canisius A, Orning C, Lackner KJ. Induction of tissue factor expression by anti-ß2-glycoprotein I is mediated by tumor necrosis factor a. J Thromb Thrombolysis. 2020 Feb; 49(2):228-234.

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Hollerbach A, Müller-Calleja N, Ritter S, Häuser F, Canisius A, Orning C, Jurk K, Lackner KJ. Platelet Activation by Antiphospholipid Antibodies Depends on Epitope Specificity and is Prevented by mTOR Inhibitors. Thromb Haemost. 2019 Jul; 119(7):1147-1153.

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Hanly JG, Li Q, Su L, Urowitz MB, Gordon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg DA, Rahman A, Merrill JT, Fortin PR, Gladman DD, Bruce IN, Petri M, Ginzler EM, Dooley MA, Steinsson K, Ramsey-Goldman R, Zoma AA, Manzi S, Nived O, Jonsen A, Khamashta MA, Alarcón GS, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Ramos-Casals M, Lim SS, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askanase A, Theriault C, Farewell V. Psychosis in Systemic Lupus Erythematosus: Results From an International Inception Cohort Study. Arthritis Rheumatol. 2019 02; 71(2):281-289.

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Wahezi DM, Ilowite NT, Wu XX, Pelkmans L, Laat B, Schanberg LE, Rand JH. Annexin A5 anticoagulant activity in children with systemic lupus erythematosus and the association with antibodies to domain I of ß2-glycoprotein I. Lupus. 2013 Jun; 22(7):702-11.

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Ede K, Hwang KK, Wu CC, Wu M, Yang YH, Lin WS, Chien D, Chen PC, Tsao BP, McCurdy DK, Chen PP. Plasmin immunization preferentially induces potentially prothrombotic IgG anticardiolipin antibodies in MRL/MpJ mice. Arthritis Rheum. 2009 Oct; 60(10):3108-17.

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Lee RM, Emlen W, Scott JR, Branch DW, Silver RM. Anti-beta2-glycoprotein I antibodies in women with recurrent spontaneous abortion, unexplained fetal death, and antiphospholipid syndrome. Am J Obstet Gynecol. 1999 Sep; 181(3):642-8.

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Gharavi AE, Cucurull E, Tang H, Silver RM, Branch DW. Effect of antiphospholipid antibodies on beta(2) glycoprotein I-phospholipid Interaction. Am J Reprod Immunol. 1998 May; 39(5):310-5.

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