"Nitrosourea Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of compounds in which the core molecule is R-NO, where R is UREA.
| Descriptor ID |
D009607
|
| MeSH Number(s) |
D02.654.692 D02.948.594
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nitrosourea Compounds".
Below are MeSH descriptors whose meaning is more specific than "Nitrosourea Compounds".
This graph shows the total number of publications written about "Nitrosourea Compounds" by people in this website by year, and whether "Nitrosourea Compounds" was a major or minor topic of these publications.
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Below are the most recent publications written about "Nitrosourea Compounds" by people in Profiles.
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Immunomodulatory effects of nitrosoureas on the phenotype and functions of T cells in the thymus and periphery. Immunopharmacology. 1990 Nov-Dec; 20(3):153-64.
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Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl- 1-(3-(2-chloroethyl)-3-nitrosoureido) ethylphosphonate-S10036. Anticancer Res. 1989 Nov-Dec; 9(6):1617-22.
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Carbamoylation of glutathione reductase and changes in cellular and chromosome morphology in a rat cell line resistant to nitrogen mustards but collaterally sensitive to nitrosoureas. Cancer Res. 1985 May; 45(5):2326-33.
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Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Pathways of aqueous decomposition and pharmacological characteristics of new anticancer disulfide-linked nitrosoureas. Biochem Pharmacol. 1985 Apr 01; 34(7):1015-24.
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Biochemical and cytotoxic properties of the isomeric forms of N,N'-bis[N-2-chloroethyl)-N-nitrosocarbamoyl] cystamine. Biochem Pharmacol. 1984 Aug 15; 33(16):2575-80.
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Repair of DNA alkylation induced in L1210 leukemia and murine bone marrow by three chloroethylnitrosoureas. Cancer Res. 1982 Jul; 42(7):2605-8.
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Correlation of nitrosourea murine bone marrow toxicity with deoxyribonucleic acid alkylation and chromatin binding sites. Biochem Pharmacol. 1982 May 01; 31(9):1671-9.
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Selective cytotoxicity of haloethylnitrosoureas in a carcinoma cell line resistant to bifunctional nitrogen mustards. Mol Pharmacol. 1982 May; 21(3):729-38.
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Enhancement of nitrosourea cytotoxicity in vitro using hydrocortisone. Biochem Pharmacol. 1982 Mar 15; 31(6):1179-80.
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Chemotherapy of malignant melanoma. J Am Acad Dermatol. 1982 Mar; 6(3):412-6.