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    • The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.
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The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.

The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol Cancer Ther. 2005 Mar; 4(3):443-9.

View in: PubMed

subject areas
  • Animals
  • Antineoplastic Agents
  • Apoptosis
  • Apoptosis Regulatory Proteins
  • Bcl-2-Like Protein 11
  • Blotting, Western
  • Boronic Acids
  • Bortezomib
  • Carrier Proteins
  • Cell Line
  • Cell Line, Tumor
  • Cell Survival
  • Cells, Cultured
  • Colonic Neoplasms
  • Dose-Response Relationship, Drug
  • Down-Regulation
  • Fibroblasts
  • Green Fluorescent Proteins
  • Humans
  • Immunoprecipitation
  • Male
  • Membrane Glycoproteins
  • Membrane Proteins
  • Mice
  • Mitochondrial Proteins
  • Peptide Fragments
  • Plasmids
  • Prostatic Neoplasms
  • Proteasome Endopeptidase Complex
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • Pyrazines
  • Reverse Transcriptase Polymerase Chain Reaction
  • RNA
  • RNA Interference
  • TNF-Related Apoptosis-Inducing Ligand
  • Transfection
  • Tumor Necrosis Factor-alpha

authors with profiles
  • Andrew S Kraft