X-Box Binding Protein 1

"X-Box Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.

Descriptor ID	D000071717
MeSH Number(s)	D12.776.260.108.937 D12.776.930.127.937
Concept/Terms	X-Box Binding Protein 1 X-Box Binding Protein 1 X Box Binding Protein 1 TREB5 Protein Tax-Responsive Element-Binding Protein 5 Tax Responsive Element Binding Protein 5 XBP-1 Protein XBP 1 Protein TREB-5 Protein TREB 5 Protein XBP2 Protein

Below are MeSH descriptors whose meaning is more general than "X-Box Binding Protein 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
X-Box Binding Protein 1 [D12.776.260.108.937]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
X-Box Binding Protein 1 [D12.776.930.127.937]

Below are MeSH descriptors whose meaning is related to "X-Box Binding Protein 1".

Below are MeSH descriptors whose meaning is more specific than "X-Box Binding Protein 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "X-Box Binding Protein 1" by people in this website by year, and whether "X-Box Binding Protein 1" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 3 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	1	1
2012	0	3	3
2013	0	1	1
2018	1	0	1
2021	1	0	1
2022	1	0	1

Below are the most recent publications written about "X-Box Binding Protein 1" by people in Profiles.

Liu X, Taylor SA, Gromer KD, Zhang D, Hubchak SC, LeCuyer BE, Iwawaki T, Shi Z, Rockey DC, Green RM. Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box binding protein 1. PLoS One. 2022; 17(1):e0261789.

View in: PubMed
Choi HJ, Tang CA, Tian L, Wu Y, Sofi MH, Ticer T, Schutt SD, Hu CA, Yu XZ. XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1a-Dependent Decay. Front Immunol. 2021; 12:705484.

View in: PubMed
Schutt SD, Wu Y, Tang CH, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CC, Yu XZ. Inhibition of the IRE-1a/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice. Blood Adv. 2018 02 27; 2(4):414-427.

View in: PubMed
Hua Y, White-Gilbertson S, Kellner J, Rachidi S, Usmani SZ, Chiosis G, Depinho R, Li Z, Liu B. Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res. 2013 Nov 15; 19(22):6242-51.

View in: PubMed
Dioufa N, Chatzistamou I, Farmaki E, Papavassiliou AG, Kiaris H. p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress. Exp Biol Med (Maywood). 2012 Oct; 237(10):1173-80.

View in: PubMed
Pehar M, Jonas MC, Hare TM, Puglielli L. SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway. J Biol Chem. 2012 Aug 24; 287(35):29921-30.

View in: PubMed
Wang G, Liu G, Wang X, Sethi S, Ali-Fehmi R, Abrams J, Zheng Z, Zhang K, Ethier S, Yang ZQ. ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways. BMC Cancer. 2012 Jun 08; 12:225.

View in: PubMed
Jiao P, Ma J, Feng B, Zhang H, Diehl JA, Chin YE, Yan W, Xu H. FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKß pathways. Obesity (Silver Spring). 2011 Mar; 19(3):483-91.

View in: PubMed
Dally S, Monceau V, Corvazier E, Bredoux R, Raies A, Bobe R, del Monte F, Enouf J. Compartmentalized expression of three novel sarco/endoplasmic reticulum Ca2+ATPase 3 isoforms including the switch to ER stress, SERCA3f, in non-failing and failing human heart. Cell Calcium. 2009 Feb; 45(2):144-54.

View in: PubMed

People

Explore

Similar Concepts

Top Journals