Transcription Factor AP-1
"Transcription Factor AP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
| Descriptor ID |
D018808
|
| MeSH Number(s) |
D12.776.260.108.875 D12.776.930.127.875
|
| Concept/Terms |
Transcription Factor AP-1- Transcription Factor AP-1
- Transcription Factor AP 1
- AP-1 Enhancer-Binding Protein
- Enhancer-Binding Protein, AP-1
- AP-1
- Activator Protein-1
- Activator Protein 1
- AP-1 Enhancer Binding Protein
- AP 1 Enhancer Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-1".
This graph shows the total number of publications written about "Transcription Factor AP-1" by people in this website by year, and whether "Transcription Factor AP-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 3 | 3 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 5 | 7 |
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 2 | 3 |
| 2013 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Transcription Factor AP-1" by people in Profiles.
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TGF-?1 Suppresses IL-33-Induced Mast Cell Function. J Immunol. 2017 08 01; 199(3):866-873.
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Transforming growth factor ?1 (TGF?1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis. J Biol Chem. 2017 06 23; 292(25):10490-10519.
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The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma. Mol Cancer Ther. 2016 05; 15(5):1018-28.
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Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2. J Mol Cell Cardiol. 2015 Jul; 84:143-53.
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Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse. J Clin Invest. 2013 Oct; 123(10):4344-58.
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Transcriptional regulation of increased CCL2 expression in pulmonary fibrosis involves nuclear factor-?B and activator protein-1. Int J Biochem Cell Biol. 2013 Jul; 45(7):1366-76.
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Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism. J Biol Chem. 2010 Feb 05; 285(6):3916-3927.
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beta-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes. J Mol Cell Cardiol. 2010 Feb; 48(2):342-51.
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Siva-1 promotes K-48 polyubiquitination of TRAF2 and inhibits TCR-mediated activation of NF-kappaB. J Environ Pathol Toxicol Oncol. 2009; 28(1):25-38.
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ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. Cancer Res. 2008 Nov 01; 68(21):8908-17.