"Patched Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
| Descriptor ID |
D000072079
|
| MeSH Number(s) |
D12.776.543.750.058 D12.776.624.776.633
|
| Concept/Terms |
Patched Receptors- Patched Receptors
- Receptors, Patched
- Patched Sonic Hedgehog Receptors
- Patched Receptor
- Receptor, Patched
- Patched Protein
|
Below are MeSH descriptors whose meaning is more general than "Patched Receptors".
Below are MeSH descriptors whose meaning is more specific than "Patched Receptors".
This graph shows the total number of publications written about "Patched Receptors" by people in this website by year, and whether "Patched Receptors" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Patched Receptors" by people in Profiles.
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Taniguchi E, Cho MJ, Arenkiel BR, Hansen MS, Rivera OJ, McCleish AT, Qualman SJ, Guttridge DC, Scott MP, Capecchi MR, Keller C. Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma. Pediatr Blood Cancer. 2009 Aug; 53(2):136-44.
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Morales CR, Zeng J, El Alfy M, Barth JL, Chintalapudi MR, McCarthy RA, Incardona JP, Argraves WS. Epithelial trafficking of Sonic hedgehog by megalin. J Histochem Cytochem. 2006 Oct; 54(10):1115-27.