Retinoblastoma-Like Protein p130
"Retinoblastoma-Like Protein p130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
| Descriptor ID |
D050717
|
| MeSH Number(s) |
D12.776.624.776.735 D12.776.660.794 D12.776.744.755
|
| Concept/Terms |
Retinoblastoma-Like Protein p130- Retinoblastoma-Like Protein p130
- p130, Retinoblastoma-Like Protein
- Retinoblastoma Like Protein p130
- Retinoblastoma-Like Protein 2
- Retinoblastoma Like Protein 2
- RBL2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Like Protein p130".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Like Protein p130".
This graph shows the total number of publications written about "Retinoblastoma-Like Protein p130" by people in this website by year, and whether "Retinoblastoma-Like Protein p130" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoblastoma-Like Protein p130" by people in Profiles.
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Cell cycle kinases as therapeutic targets for cancer. Nat Rev Drug Discov. 2009 Jul; 8(7):547-66.
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Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2. J Virol. 2007 Dec; 81(23):13191-9.
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Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src. J Mol Cell Cardiol. 2003 Jun; 35(6):671-83.
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Protein phosphatase-2A regulates endothelial cell motility and both the phosphorylation and the stability of focal adhesion complexes. Int J Cancer. 2002 Jul 20; 100(3):276-82.
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Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. Mol Cell Biol. 2000 May; 20(10):3626-32.
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Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth. Cell Growth Differ. 1998 Apr; 9(4):297-303.
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The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. Mol Cell Biol. 1996 Dec; 16(12):6965-76.