Promyelocytic Leukemia Protein
"Promyelocytic Leukemia Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
| Descriptor ID |
D000071156
|
| MeSH Number(s) |
D12.776.624.776.654 D12.776.660.745 D12.776.930.713 D12.776.934.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Promyelocytic Leukemia Protein".
Below are MeSH descriptors whose meaning is more specific than "Promyelocytic Leukemia Protein".
This graph shows the total number of publications written about "Promyelocytic Leukemia Protein" by people in this website by year, and whether "Promyelocytic Leukemia Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Promyelocytic Leukemia Protein" by people in Profiles.
-
Stable overexpression of PML alters regulation of cell cycle progression in HeLa cells. Carcinogenesis. 1997 Nov; 18(11):2063-9.
-
The biologic function of PML and its role in acute promyelocytic leukemia. Leuk Lymphoma. 1996 Oct; 23(3-4):277-85.
-
Cytogenetics, gene fusions, and cancer. Ann Clin Lab Sci. 1995 Sep-Oct; 25(5):389-93.