Combinatorial Chemistry Techniques
"Combinatorial Chemistry Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale.
| Descriptor ID |
D020650
|
| MeSH Number(s) |
E05.197.312 J01.897.836.249.249
|
| Concept/Terms |
Combinatorial Chemistry Techniques- Combinatorial Chemistry Techniques
- Techniques, Combinatorial Chemistry
- Chemistry Technique, Combinatorial
- Combinatorial Chemistry Technique
- Technics, Combinatorial Chemistry
- Chemistry Technic, Combinatorial
- Chemistry Technics, Combinatorial
- Combinatorial Chemistry Technic
- Combinatorial Chemistry Technics
- Technic, Combinatorial Chemistry
- Chemistry Techniques, Combinatorial
- Technique, Combinatorial Chemistry
|
Below are MeSH descriptors whose meaning is more general than "Combinatorial Chemistry Techniques".
Below are MeSH descriptors whose meaning is more specific than "Combinatorial Chemistry Techniques".
This graph shows the total number of publications written about "Combinatorial Chemistry Techniques" by people in this website by year, and whether "Combinatorial Chemistry Techniques" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2007 | 0 | 4 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Combinatorial Chemistry Techniques" by people in Profiles.
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Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma. Leukemia. 2019 04; 33(4):1011-1022.
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Synthesis of optically active 4-substituted 2-cyclohexenones. Org Lett. 2012 Sep 07; 14(17):4394-7.
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Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation. J Med Chem. 2009 Jul 23; 52(14):4210-20.
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Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 08; 52(1):74-86.
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Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries. Chem Biol. 2008 Sep 22; 15(9):969-78.
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Use of peptide analogue diversity library beads for increased depth of proteomic analysis: application to cerebrospinal fluid. J Proteome Res. 2008 May; 7(5):1922-31.
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Pyrazolopyridines with potent activity against herpesviruses: effects of C5 substituents on antiviral activity. Bioorg Med Chem Lett. 2008 Feb 01; 18(3):1157-61.
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Novel analogs of D-e-MAPP and B13. Part 2: signature effects on bioactive sphingolipids. Bioorg Med Chem. 2008 Jan 15; 16(2):1032-45.
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Novel analogs of D-e-MAPP and B13. Part 1: synthesis and evaluation as potential anticancer agents. Bioorg Med Chem. 2008 Jan 15; 16(2):1015-31.
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Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease. J Nat Prod. 2007 Sep; 70(9):1397-405.