"Polyglutamic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide that is a homopolymer of glutamic acid.
| Descriptor ID |
D011099
|
| MeSH Number(s) |
D12.125.067.625.700 D12.125.119.409.700 D12.644.748
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Polyglutamic Acid".
Below are MeSH descriptors whose meaning is more specific than "Polyglutamic Acid".
This graph shows the total number of publications written about "Polyglutamic Acid" by people in this website by year, and whether "Polyglutamic Acid" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyglutamic Acid" by people in Profiles.
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Mauritz R, Peters GJ, Priest DG, Assaraf YG, Drori S, Kathmann I, Noordhuis P, Bunni MA, Rosowsky A, Schornagel JH, Pinedo HM, Jansen G. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis. Biochem Pharmacol. 2002 Jan 15; 63(2):105-15.
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Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. Blood. 1994 Jul 15; 84(2):564-9.
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Duke EJ, Priest DG. Regulation of drosophila folylpolyglutamates during development. Mol Cell Biochem. 1990 Sep 21; 97(2):187-8.
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Samuels LL, Goutas LJ, Priest DG, Piper JR, Sirotnak FM. Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse. Cancer Res. 1986 May; 46(5):2230-5.
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Priest DG, Veronee CD, Mangum M, Bednarek JM, Doig MT. Comparison of folylpolyglutamate hydrolases of mouse liver, kidney, muscle and brain. Mol Cell Biochem. 1982 Mar 19; 43(2):81-7.
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Priest DG, Mangum M. Relative affinity of 5,10-methylenetetrahydrofolylpolyglutamates for the Lactobacillus casei thymidylate synthetase-5-fluorodeoxyuridylate binary complex. Arch Biochem Biophys. 1981 Aug; 210(1):118-23.