Pulmonary Surfactant-Associated Protein C
"Pulmonary Surfactant-Associated Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.
| Descriptor ID |
D037721
|
| MeSH Number(s) |
D12.776.543.717 D12.776.816.750 D12.776.823.186
|
| Concept/Terms |
Pulmonary Surfactant-Associated Protein C- Pulmonary Surfactant-Associated Protein C
- Pulmonary Surfactant Associated Protein C
- Surfactant Polypeptide SP-C
- SP-C, Surfactant Polypeptide
- Surfactant Polypeptide SP C
- SP-C protein
- SP C protein
- Pulmonary Surfactant Protein C
- Pulmonary Surfactant-Associated Protein SP-C
- Pulmonary Surfactant Associated Protein SP C
|
Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein C".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein C".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein C" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein C" by people in Profiles.
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Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):845-54.
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Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury. Respir Res. 2013 Feb 12; 14:19.
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Hypoxia up-regulates expression of hemoglobin in alveolar epithelial cells. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):439-47.
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Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol. 2009 Jul; 297(1):L64-72.
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Mechanical ventilation down-regulates surfactant protein A and keratinocyte growth factor expression in premature rabbits. Pediatr Res. 2007 Sep; 62(3):277-82.
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Surface properties of sulfur- and ether-linked phosphonolipids with and without purified hydrophobic lung surfactant proteins. Chem Phys Lipids. 2005 Oct; 137(1-2):77-93.
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Deacylated pulmonary surfactant protein SP-C transforms from alpha-helical to amyloid fibril structure via a pH-dependent mechanism: an infrared structural investigation. Biophys J. 2003 Oct; 85(4):2417-29.