Receptors, G-Protein-Coupled

"Receptors, G-Protein-Coupled" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.

Descriptor ID	D043562
MeSH Number(s)	D12.776.543.750.695
Concept/Terms	Receptors, G-Protein-Coupled Receptors, G-Protein-Coupled Receptors, G Protein Coupled G-Protein-Coupled Receptors G Protein Coupled Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, G-Protein-Coupled".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]

Below are MeSH descriptors whose meaning is related to "Receptors, G-Protein-Coupled".

Below are MeSH descriptors whose meaning is more specific than "Receptors, G-Protein-Coupled".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, G-Protein-Coupled" by people in this website by year, and whether "Receptors, G-Protein-Coupled" was a major or minor topic of these publications.

Bar chart showing 121 publications over 29 distinct years, with a maximum of 8 publications in 2005 and 2012 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	2	2
1994	0	1	1
1995	0	1	1
1996	2	2	4
1998	2	0	2
1999	0	1	1
2000	0	1	1
2001	1	4	5
2002	3	1	4
2003	5	2	7
2004	1	3	4
2005	6	2	8
2006	4	2	6
2007	3	1	4
2008	3	1	4
2009	3	3	6
2010	2	3	5
2011	6	1	7
2012	4	4	8
2013	1	4	5
2014	3	2	5
2015	7	1	8
2016	5	1	6
2017	3	0	3
2018	4	0	4
2019	1	0	1
2020	4	1	5
2021	2	0	2
2022	1	1	2

Below are the most recent publications written about "Receptors, G-Protein-Coupled" by people in Profiles.

Hathaway-Schrader JD, Novince CM. GPR65, a novel regulator of helper T-cell polarization in inflammatory bowel disease. Clin Transl Med. 2022 06; 12(6):e857.

View in: PubMed
Chaki S, Alkanfari I, Roy S, Amponnawarat A, Hui Y, Oskeritzian CA, Ali H. Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells. Front Immunol. 2021; 12:803335.

View in: PubMed
Syed M, Kammala AK, Callahan B, Oskeritzian CA, Subramanian H. Lactic acid suppresses MRGPRX2 mediated mast cell responses. Cell Immunol. 2021 10; 368:104422.

View in: PubMed
Killoran MP, Levin S, Boursier ME, Zimmerman K, Hurst R, Hall MP, Machleidt T, Kirkland TA, Friedman Ohana R. An Integrated Approach toward NanoBRET Tracers for Analysis of GPCR Ligand Engagement. Molecules. 2021 May 12; 26(10).

View in: PubMed
van Gastel J, Leysen H, Boddaert J, Vangenechten L, Luttrell LM, Martin B, Maudsley S. Aging-related modifications to G protein-coupled receptor signaling diversity. Pharmacol Ther. 2021 07; 223:107793.

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Lu Z, Li Y, Syn WK, Li AJ, Ritter WS, Wank SA, Lopes-Virella MF, Huang Y. GPR40 deficiency is associated with hepatic FAT/CD36 upregulation, steatosis, inflammation, and cell injury in C57BL/6 mice. Am J Physiol Endocrinol Metab. 2021 01 01; 320(1):E30-E42.

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Ahn S, Shenoy SK, Luttrell LM, Lefkowitz RJ. SnapShot: ß-Arrestin Functions. Cell. 2020 09 03; 182(5):1362-1362.e1.

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Liu S, Luttrell LM, Premont RT, Rockey DC. ß-Arrestin2 is a critical component of the GPCR-eNOS signalosome. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11483-11492.

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Callahan BN, Kammala AK, Syed M, Yang C, Occhiuto CJ, Nellutla R, Chumanevich AP, Oskeritzian CA, Das R, Subramanian H. Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses. Front Immunol. 2020; 11:703.

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Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives EA, Chang G, Ghosh P, Kufareva I. Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16394-16403.

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