Interferon Regulatory Factor-7
"Interferon Regulatory Factor-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.
Descriptor ID |
D050839
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MeSH Number(s) |
D12.644.360.024.302.437 D12.776.157.057.050.437 D12.776.260.504.437 D12.776.476.024.385.437 D12.776.744.631 D12.776.930.332.437
|
Concept/Terms |
IRF-7C Transcription Factor- IRF-7C Transcription Factor
- Factor, IRF-7C Transcription
- IRF 7C Transcription Factor
- Transcription Factor, IRF-7C
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Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-7".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-7".
This graph shows the total number of publications written about "Interferon Regulatory Factor-7" by people in this website by year, and whether "Interferon Regulatory Factor-7" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2011 | 2 | 0 | 2 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-7" by people in Profiles.
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SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3798-E3807.
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Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis. 2012 Jan; 71(1):114-9.
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Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum. 2011 Mar; 63(3):749-54.
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RIG-I mediates the co-induction of tumor necrosis factor and type I interferon elicited by myxoma virus in primary human macrophages. PLoS Pathog. 2008 Jul 11; 4(7):e1000099.