Interferon Regulatory Factor-7
"Interferon Regulatory Factor-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.
| Descriptor ID |
D050839
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| MeSH Number(s) |
D12.644.360.024.302.437 D12.776.157.057.050.437 D12.776.260.504.437 D12.776.476.024.385.437 D12.776.744.631 D12.776.930.332.437
|
| Concept/Terms |
IRF-7C Transcription Factor- IRF-7C Transcription Factor
- Factor, IRF-7C Transcription
- IRF 7C Transcription Factor
- Transcription Factor, IRF-7C
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-7".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-7".
This graph shows the total number of publications written about "Interferon Regulatory Factor-7" by people in this website by year, and whether "Interferon Regulatory Factor-7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-7" by people in Profiles.
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Chen S, Bonifati S, Qin Z, St Gelais C, Kodigepalli KM, Barrett BS, Kim SH, Antonucci JM, Ladner KJ, Buzovetsky O, Knecht KM, Xiong Y, Yount JS, Guttridge DC, Santiago ML, Wu L. SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3798-E3807.
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Carmona FD, Gutala R, Simeón CP, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E, García-Hernández FJ, García de la Peña P, Fernández-Castro M, Martínez-Estupiñán L, Egurbide MV, Tsao BP, Gourh P, Agarwal SK, Assassi S, Mayes MD, Arnett FC, Tan FK, Martín J. Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis. 2012 Jan; 71(1):114-9.
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Fu Q, Zhao J, Qian X, Wong JL, Kaufman KM, Yu CY, Mok MY, Harley JB, Guthridge JM, Song YW, Cho SK, Bae SC, Grossman JM, Hahn BH, Arnett FC, Shen N, Tsao BP. Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum. 2011 Mar; 63(3):749-54.
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Wang F, Gao X, Barrett JW, Shao Q, Bartee E, Mohamed MR, Rahman M, Werden S, Irvine T, Cao J, Dekaban GA, McFadden G. RIG-I mediates the co-induction of tumor necrosis factor and type I interferon elicited by myxoma virus in primary human macrophages. PLoS Pathog. 2008 Jul 11; 4(7):e1000099.