Toll-Like Receptor 4

"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.

Descriptor ID	D051197
MeSH Number(s)	D12.776.543.750.705.910.500.400
Concept/Terms	Toll-Like Receptor 4 Toll-Like Receptor 4 Toll Like Receptor 4 Toll-4 Receptor Toll 4 Receptor TLR4 Receptor Receptor, TLR4

Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Pattern Recognition [D12.776.543.750.705.910]
Toll-Like Receptors [D12.776.543.750.705.910.500]
Toll-Like Receptor 4 [D12.776.543.750.705.910.500.400]

Below are MeSH descriptors whose meaning is related to "Toll-Like Receptor 4".

Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.

Bar chart showing 68 publications over 18 distinct years, with a maximum of 12 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2004	0	2	2
2005	0	2	2
2006	0	1	1
2007	3	2	5
2008	0	2	2
2009	4	0	4
2010	3	1	4
2011	5	3	8
2012	3	2	5
2013	1	2	3
2014	1	4	5
2015	8	4	12
2016	2	1	3
2017	2	1	3
2018	4	2	6
2020	0	1	1
2021	1	0	1

Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.

Sundararaj K, Rodgers J, Angel P, Wolf B, Nowling TK. The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Immunology. 2021 04; 162(4):418-433.

View in: PubMed
Mondal A, Bose D, Saha P, Sarkar S, Seth R, Kimono D, Albadrani M, Nagarkatti M, Nagarkatti P, Chatterjee S. Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. J Neuroinflammation. 2020 Jul 04; 17(1):201.

View in: PubMed
Mayall RM, Renaud-Young M, Gawron E, Luong S, Creager S, Birss VI. Enhanced Signal Amplification in a Toll-like Receptor-4 Biosensor Utilizing Ferrocene-Terminated Mixed Monolayers. ACS Sens. 2019 01 25; 4(1):143-151.

View in: PubMed
Dattaroy D, Seth RK, Sarkar S, Kimono D, Albadrani M, Chandrashekaran V, Hasson FA, Singh UP, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48.

View in: PubMed
Abdul Y, Abdelsaid M, Li W, Webb RC, Sullivan JC, Dong G, Ergul A. Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4. Mol Neurobiol. 2019 Mar; 56(3):1607-1617.

View in: PubMed
Ou T, Lilly M, Jiang W. The Pathologic Role of Toll-Like Receptor 4 in Prostate Cancer. Front Immunol. 2018; 9:1188.

View in: PubMed
Dimitrova E, Caromile LA, Laubenbacher R, Shapiro LH. The innate immune response to ischemic injury: a multiscale modeling perspective. BMC Syst Biol. 2018 04 10; 12(1):50.

View in: PubMed
Ahmad R, Al-Roub A, Kochumon S, Akther N, Thomas R, Kumari M, Koshy MS, Tiss A, Hannun YA, Tuomilehto J, Sindhu S, Rosen ED. The Synergy between Palmitate and TNF-a for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 2018 05 15; 200(10):3599-3611.

View in: PubMed
Brown KT, Levis SC, O'Neill CE, Northcutt AL, Fabisiak TJ, Watkins LR, Bachtell RK. Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking. Brain Behav Immun. 2018 Jan; 67:130-138.

View in: PubMed
Nicholas DA, Zhang K, Hung C, Glasgow S, Aruni AW, Unternaehrer J, Payne KJ, Langridge WHR, De Leon M. Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1ß. PLoS One. 2017; 12(5):e0176793.

View in: PubMed

People

Explore

Similar Concepts

Top Journals