Gonadotropin-Releasing Hormone

"Gonadotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.

Descriptor ID	D007987
MeSH Number(s)	D06.472.699.327.740.320 D12.644.400.400.740.320 D12.644.456.460 D12.644.548.365.740.320 D12.776.631.650.405.740.320
Concept/Terms	Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gonadotropin Releasing Hormone Gn-RH Gonadoliberin LHFSH Releasing Hormone Releasing Hormone, LHFSH LH-RH LFRH LH-Releasing Hormone LH Releasing Hormone LH-FSH Releasing Hormone LH FSH Releasing Hormone LHFSHRH LHRH Luliberin Gonadorelin Luteinizing Hormone-Releasing Hormone Luteinizing Hormone Releasing Hormone FSH-Releasing Hormone FSH Releasing Hormone GnRH Factrel Factrel Cystorelin Cystorelin Gonadorelin Hydrochloride Gonadorelin Hydrochloride Kryptocur Kryptocur Dirigestran Dirigestran Gonadorelin Acetate Gonadorelin Acetate

Below are MeSH descriptors whose meaning is more general than "Gonadotropin-Releasing Hormone".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Hypothalamic Hormones [D06.472.699.327]
Pituitary Hormone-Releasing Hormones [D06.472.699.327.740]
Gonadotropin-Releasing Hormone [D06.472.699.327.740.320]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Hypothalamic Hormones [D12.644.400.400]
Pituitary Hormone-Releasing Hormones [D12.644.400.400.740]
Gonadotropin-Releasing Hormone [D12.644.400.400.740.320]
Oligopeptides [D12.644.456]
Gonadotropin-Releasing Hormone [D12.644.456.460]
Peptide Hormones [D12.644.548]
Hypothalamic Hormones [D12.644.548.365]
Pituitary Hormone-Releasing Hormones [D12.644.548.365.740]
Gonadotropin-Releasing Hormone [D12.644.548.365.740.320]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Hypothalamic Hormones [D12.776.631.650.405]
Pituitary Hormone-Releasing Hormones [D12.776.631.650.405.740]
Gonadotropin-Releasing Hormone [D12.776.631.650.405.740.320]

Below are MeSH descriptors whose meaning is more specific than "Gonadotropin-Releasing Hormone".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gonadotropin-Releasing Hormone" by people in this website by year, and whether "Gonadotropin-Releasing Hormone" was a major or minor topic of these publications.

Bar chart showing 22 publications over 14 distinct years, with a maximum of 3 publications in 1997 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	2	1	3
1999	1	1	2
2000	2	0	2
2002	1	1	2
2007	0	1	1
2008	1	0	1
2009	1	0	1
2011	1	0	1
2012	1	0	1
2013	1	0	1
2015	1	1	2
2017	1	0	1
2018	1	0	1
2019	2	1	3

Below are the most recent publications written about "Gonadotropin-Releasing Hormone" by people in Profiles.

Crawford ED, Twardowski PW, Concepcion RS, Hafron JM, Harris RG, Moul JW, Gordan LN, Petrylak DP, Atkinson SN, Boldt-Houle DM, Keane TE, Higano CS, Henderson RJ, Kader AK, Hussain MH, Shore ND. The Impact of Late Luteinizing Hormone-Releasing Hormone Agonist Dosing on Testosterone Suppression in Patients with Prostate Cancer: An Analysis of United States Clinical Data. J Urol. 2020 Apr; 203(4):743-750.

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Matheson E, Bain J. Hirsutism in Women. Am Fam Physician. 2019 08 01; 100(3):168-175.

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Crawford ED, Tombal B, Keane T, Boccardo F, Miller K, Shore N, Moul JW, Damber JE, Collette L, Persson BE. FSH suppression and tumour control in patients with prostate cancer during androgen deprivation with a GnRH agonist or antagonist. Scand J Urol. 2018 Oct - Dec; 52(5-6):349-357.

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Kiaris H, Chatzistamou I. Inhibition of tumor growth by agonists of growth hormone-releasing hormone. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):11876-11878.

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Greiman AK, Keane TE. Approach to Androgen Deprivation in the Prostate Cancer Patient with Pre-existing Cardiovascular Disease. Curr Urol Rep. 2017 Jun; 18(6):41.

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Kaugars KE, Rivers CI, Saha MS, Heideman PD. Genetic variation in total number and locations of GnRH neurons identified using in situ hybridization in a wild-source population. J Exp Zool A Ecol Genet Physiol. 2016 Feb; 325(2):106-15.

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Yu EY, Li H, Higano CS, Agarwal N, Pal SK, Alva A, Heath EI, Lam ET, Gupta S, Lilly MB, Inoue Y, Chi KN, Vogelzang NJ, Quinn DI, Cheng HH, Plymate SR, Hussain M, Tangen CM, Thompson IM. SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer. J Clin Oncol. 2015 May 10; 33(14):1601-8.

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Patrick E, Whitson M, Smith A, Parnell J, Thomas SE, Blankenship CC. GnRH receptor antagonists for prostate cancer. JAAPA. 2013 Jul; 26(7):51-2.

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Schröder F, Crawford ED, Axcrona K, Payne H, Keane TE. Androgen deprivation therapy: past, present and future. BJU Int. 2012 Jun; 109 Suppl 6:1-12.

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Kraft AS, Garrett-Mayer E, Wahlquist AE, Golshayan A, Chen CS, Butler W, Bearden J, Lilly M. Combination therapy of recurrent prostate cancer with the proteasome inhibitor bortezomib plus hormone blockade. Cancer Biol Ther. 2011 Jul 15; 12(2):119-24.

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