"Lectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
| Descriptor ID |
D037102
|
| MeSH Number(s) |
D12.776.503
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lectins".
Below are MeSH descriptors whose meaning is more specific than "Lectins".
This graph shows the total number of publications written about "Lectins" by people in this website by year, and whether "Lectins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 3 | 2 | 5 |
| 1997 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lectins" by people in Profiles.
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Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. Mol Cell Proteomics. 2021; 20:100012.
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Monodisperse Sequence-Controlled a-l-Fucosylated Glycooligomers and Their Multivalent Inhibitory Effects on LecB. Macromol Biosci. 2018 12; 18(12):e1800337.
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Biomarker analysis of fucosylated kininogen through depletion of lectin reactive heterophilic antibodies in hepatocellular carcinoma. J Immunol Methods. 2018 11; 462:59-64.
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Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge. Int Arch Allergy Immunol. 2018; 177(1):16-28.
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Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. Sci Rep. 2017 06 02; 7(1):2707.
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Upregulation of glycans containing 3' fucose in a subset of pancreatic cancers uncovered using fusion-tagged lectins. J Proteome Res. 2015 Jun 05; 14(6):2594-605.
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Characterization of the Grp94/OS-9 chaperone-lectin complex. J Mol Biol. 2014 Oct 23; 426(21):3590-605.
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Lectin-reactive anti-a-gal in patients with Crohn's disease: correlation with clinical phenotypes. Inflamm Bowel Dis. 2013 Dec; 19(13):2796-800.
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Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. PLoS One. 2013; 8(6):e67894.
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N-linked glycosylation of the liver cancer biomarker GP73. J Cell Biochem. 2008 May 01; 104(1):136-49.