"Immediate-Early Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
| Descriptor ID |
D017874
|
| MeSH Number(s) |
D12.776.460 D12.776.964.925.968
|
| Concept/Terms |
Immediate-Early Proteins- Immediate-Early Proteins
- Immediate Early Proteins
- Proteins, Immediate-Early
- Proteins, Immediate Early
|
Below are MeSH descriptors whose meaning is more general than "Immediate-Early Proteins".
Below are MeSH descriptors whose meaning is more specific than "Immediate-Early Proteins".
This graph shows the total number of publications written about "Immediate-Early Proteins" by people in this website by year, and whether "Immediate-Early Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 5 | 1 | 6 |
| 1996 | 4 | 0 | 4 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 2 | 4 |
| 1999 | 1 | 0 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 2 | 1 | 3 |
| 2004 | 3 | 1 | 4 |
| 2005 | 2 | 1 | 3 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 2 | 3 |
| 2008 | 3 | 0 | 3 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immediate-Early Proteins" by people in Profiles.
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Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling. Circulation. 2012 Oct 30; 126(18):2208-19.
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Proteomic analysis of CTGF-activated lung fibroblasts: identification of IQGAP1 as a key player in lung fibroblast migration. Am J Physiol Lung Cell Mol Physiol. 2008 Oct; 295(4):L603-11.
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Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes. J Clin Endocrinol Metab. 2008 May; 93(5):1893-900.
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Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells. Carcinogenesis. 2008 Apr; 29(4):696-703.
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Down-regulation of collagen and connective tissue growth factor expression with hepatocyte growth factor in lung fibroblasts from white scleroderma patients via two signaling pathways. Arthritis Rheum. 2007 Oct; 56(10):3468-77.
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Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis. Arthritis Rheum. 2007 Jul; 56(7):2432-42.
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Targeted deletion of B2-kinin receptors protects against the development of diabetic nephropathy. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1026-35.
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Quantitative membrane proteomics reveals new cellular targets of viral immune modulators. PLoS Pathog. 2006 Oct; 2(10):e107.
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Pioglitazone inhibits connective tissue growth factor expression in advanced atherosclerotic plaques in low-density lipoprotein receptor-deficient mice. Atherosclerosis. 2007 May; 192(1):85-91.
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Fli1 and Ets1 have distinct roles in connective tissue growth factor/CCN2 gene regulation and induction of the profibrotic gene program. J Biol Chem. 2006 Sep 01; 281(35):25259-69.