"Thioredoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
| Descriptor ID |
D013879
|
| MeSH Number(s) |
D12.776.915
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thioredoxins".
Below are MeSH descriptors whose meaning is more specific than "Thioredoxins".
This graph shows the total number of publications written about "Thioredoxins" by people in this website by year, and whether "Thioredoxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Thioredoxins" by people in Profiles.
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Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease. J Clin Invest. 2019 05 02; 129(7):2760-2774.
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Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells. J Biol Chem. 2019 06 07; 294(23):9198-9212.
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Intake of dietary antioxidants is inversely associated with biomarkers of oxidative stress among men with prostate cancer. Br J Nutr. 2016 Jan 14; 115(1):68-74.
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Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy. PLoS One. 2014; 9(10):e110388.
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Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice. Mol Neurobiol. 2015 Apr; 51(2):766-78.
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Proteomic analysis of murine bone marrow niche microenvironment identifies thioredoxin as a novel agent for radioprotection and for enhancing donor cell reconstitution. Exp Hematol. 2013 Nov; 41(11):944-56.
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Involvement of thioredoxin domain-containing 5 in resistance to nitrosative stress. Free Radic Biol Med. 2010 Sep 01; 49(5):872-80.
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PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Res. 2010 Feb 01; 70(3):1120-9.
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PDEF is a negative regulator of colon cancer cell growth and migration. J Cell Biochem. 2009 Dec 15; 108(6):1389-98.
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Peroxiredoxin 1 and its role in cell signaling. Cell Cycle. 2009 Dec 15; 8(24):4072-8.