Nucleic Acid Synthesis Inhibitors

"Nucleic Acid Synthesis Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds that inhibit cell production of DNA or RNA.

Descriptor ID	D019384
MeSH Number(s)	D27.505.519.389.675
Concept/Terms	Nucleic Acid Synthesis Inhibitors Nucleic Acid Synthesis Inhibitors Inhibitors, Nucleic Acid Synthesis RNA Synthesis Inhibitors RNA Synthesis Inhibitors Synthesis Inhibitors, RNA Inhibitors, RNA Synthesis DNA Polymerase Inhibitors DNA Polymerase Inhibitors Inhibitors, DNA Polymerase Polymerase Inhibitors, DNA DNA Synthesis Inhibitors DNA Synthesis Inhibitors Synthesis Inhibitors, DNA Inhibitors, DNA Synthesis

Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Synthesis Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Nucleic Acid Synthesis Inhibitors [D27.505.519.389.675]

Below are MeSH descriptors whose meaning is related to "Nucleic Acid Synthesis Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Synthesis Inhibitors".

Nucleic Acid Synthesis Inhibitors
Reverse Transcriptase Inhibitors

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nucleic Acid Synthesis Inhibitors" by people in this website by year, and whether "Nucleic Acid Synthesis Inhibitors" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2002 and 2005 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	1	1
1997	1	0	1
1998	0	1	1
2000	1	0	1
2002	1	1	2
2005	0	2	2
2011	1	1	2
2016	1	0	1

Below are the most recent publications written about "Nucleic Acid Synthesis Inhibitors" by people in Profiles.

Girijavallabhan V, Arasappan A, Bennett F, Chen K, Dang Q, Huang Y, Kerekes A, Nair L, Pissarnitski D, Verma V, Alvarez C, Chen P, Cole D, Esposite S, Huang Y, Hong Q, Liu Z, Pan W, Pu H, Rossman R, Truong Q, Vibulbhan B, Wang J, Zhao Z, Olsen D, Stamford A, Bogen S, Njoroge FG. 2'-Modified Guanosine Analogs for the Treatment of HCV. Nucleosides Nucleotides Nucleic Acids. 2016 Jun 02; 35(6):277-94.

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Tripathi K, Matmati N, Zheng WJ, Hannun YA, Mohanty BK. Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics. 2011 Oct; 189(2):533-47.

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Varner TR, Bookstaver PB, Rudisill CN, Albrecht H. Role of rifampin-based combination therapy for severe community-acquired Legionella pneumophila pneumonia. Ann Pharmacother. 2011 Jul; 45(7-8):967-76.

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Kondrikov D, Han HR, Block ER, Su Y. Growth and density-dependent regulation of NO synthase by the actin cytoskeleton in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2006 Jan; 290(1):L41-50.

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Chan SS, Longley MJ, Copeland WC. The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit. J Biol Chem. 2005 Sep 09; 280(36):31341-6.

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Fraser AV, Woster PM, Wallace HM. Induction of apoptosis in human leukaemic cells by IPENSpm, a novel polyamine analogue and anti-metabolite. Biochem J. 2002 Oct 01; 367(Pt 1):307-12.

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Golub R, Adams J, Dave S, Bennett CL. Cost-effectiveness considerations in the treatment of essential thrombocythemia. Semin Oncol. 2002 Jun; 29(3 Suppl 10):28-32.

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Fernando LP, Fernando AN, Ferlito M, Halushka PV, Cook JA. Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid. Shock. 2000 Aug; 14(2):128-33.

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Heise T, Krones A, Nath A, Jungermann K, Christ B. Parallel acceleration of phosphoenolpyruvate carboxykinase mRNA degradation and increase in ribonuclease activity induced by insulin in cultured rat hepatocytes. Biol Chem. 1998 Jul; 379(7):875-83.

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Paul RV, Wackym PS, Budisavljevic MN. Destabilization of natriuretic peptide C-receptor mRNA by phorbol myristate acetate. J Am Soc Nephrol. 1998 Jan; 9(1):26-32.

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