Glycogen Synthase Kinase 3

"Glycogen Synthase Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.

Descriptor ID	D038362
MeSH Number(s)	D05.500.117.875 D08.811.913.696.620.682.700.429.500 D08.811.913.696.620.682.700.646.625 D12.644.360.300.500 D12.776.476.081.875 D12.776.476.300.500
Concept/Terms	Glycogen Synthase Kinase 3 Glycogen Synthase Kinase 3 gsk-3 Gene Product GSK-3

Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Axin Signaling Complex [D05.500.117]
Glycogen Synthase Kinase 3 [D05.500.117.875]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Glycogen Synthase Kinases [D08.811.913.696.620.682.700.429]
Glycogen Synthase Kinase 3 [D08.811.913.696.620.682.700.429.500]
Proline-Directed Protein Kinases [D08.811.913.696.620.682.700.646]
Glycogen Synthase Kinase 3 [D08.811.913.696.620.682.700.646.625]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Glycogen Synthase Kinases [D12.644.360.300]
Glycogen Synthase Kinase 3 [D12.644.360.300.500]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Axin Signaling Complex [D12.776.476.081]
Glycogen Synthase Kinase 3 [D12.776.476.081.875]
Glycogen Synthase Kinases [D12.776.476.300]
Glycogen Synthase Kinase 3 [D12.776.476.300.500]

Below are MeSH descriptors whose meaning is related to "Glycogen Synthase Kinase 3".

Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3".

Glycogen Synthase Kinase 3
Glycogen Synthase Kinase 3 beta

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glycogen Synthase Kinase 3" by people in this website by year, and whether "Glycogen Synthase Kinase 3" was a major or minor topic of these publications.

Bar chart showing 35 publications over 20 distinct years, with a maximum of 4 publications in 2006 and 2011 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1999	0	1	1
2000	0	1	1
2001	0	1	1
2002	0	1	1
2003	1	1	2
2004	0	2	2
2005	0	2	2
2006	2	2	4
2007	1	1	2
2008	1	1	2
2009	0	1	1
2010	0	1	1
2011	1	3	4
2012	0	1	1
2013	0	1	1
2014	0	2	2
2015	0	4	4
2017	1	0	1
2021	0	1	1

Below are the most recent publications written about "Glycogen Synthase Kinase 3" by people in Profiles.

Shu Y, Hassan F, Ostrowski MC, Mehta KD. Role of hepatic PKCß in nutritional regulation of hepatic glycogen synthesis. JCI Insight. 2021 10 08; 6(19).

View in: PubMed
Gowda C, Soliman M, Kapadia M, Ding Y, Payne K, Dovat S. Casein Kinase II (CK2), Glycogen Synthase Kinase-3 (GSK-3) and Ikaros mediated regulation of leukemia. Adv Biol Regul. 2017 08; 65:16-25.

View in: PubMed
Won JS, Annamalai B, Choi S, Singh I, Singh AK. S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion. Brain Res. 2015 Oct 22; 1624:359-369.

View in: PubMed
Rajamanickam J, Annamalai B, Rahbek-Clemmensen T, Sundaramurthy S, Gether U, Jayanthi LD, Ramamoorthy S. Akt-mediated regulation of antidepressant-sensitive serotonin transporter function, cell-surface expression and phosphorylation. Biochem J. 2015 May 15; 468(1):177-90.

View in: PubMed
Das A, Miller R, Lee P, Holden CA, Lindhorst SM, Jaboin J, Vandergrift WA, Banik NL, Giglio P, Varma AK, Raizer JJ, Patel SJ. A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/ß-catenin signaling pathway. Tumour Biol. 2015 Sep; 36(9):7027-34.

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Suo D, Park J, Young S, Makita T, Deppmann CD. Coronin-1 and calcium signaling governs sympathetic final target innervation. J Neurosci. 2015 Mar 04; 35(9):3893-902.

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Le Grand M, Rovini A, Bourgarel-Rey V, Honore S, Bastonero S, Braguer D, Carre M. ROS-mediated EB1 phosphorylation through Akt/GSK3ß pathway: implication in cancer cell response to microtubule-targeting agents. Oncotarget. 2014 May 30; 5(10):3408-23.

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McBride JD, Jenkins AJ, Liu X, Zhang B, Lee K, Berry WL, Janknecht R, Griffin CT, Aston CE, Lyons TJ, Tomasek JJ, Ma JX. Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling. J Invest Dermatol. 2014 Jun; 134(6):1725-1734.

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Meng X, Su RJ, Baylink DJ, Neises A, Kiroyan JB, Lee WY, Payne KJ, Gridley DS, Wang J, Lau KH, Li G, Zhang XB. Rapid and efficient reprogramming of human fetal and adult blood CD34+ cells into mesenchymal stem cells with a single factor. Cell Res. 2013 May; 23(5):658-72.

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Preet R, Mohapatra P, Das D, Satapathy SR, Choudhuri T, Wyatt MD, Kundu CN. Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC. Carcinogenesis. 2013 Feb; 34(2):277-86.

View in: PubMed

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