"Monocrotaline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
| Descriptor ID |
D016686
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| MeSH Number(s) |
D03.132.716.500 D03.633.100.772.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Monocrotaline".
Below are MeSH descriptors whose meaning is more specific than "Monocrotaline".
This graph shows the total number of publications written about "Monocrotaline" by people in this website by year, and whether "Monocrotaline" was a major or minor topic of these publications.
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Below are the most recent publications written about "Monocrotaline" by people in Profiles.
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Regulation of kininogen gene expression and localization in the lung after monocrotaline-induced pulmonary hypertension in rats. Proc Soc Exp Biol Med. 1993 Jun; 203(2):243-50.
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Angiotensin II and monocrotaline-induced pulmonary hypertension: effect of losartan (DuP 753), a nonpeptide angiotensin type 1 receptor antagonist. J Pharmacol Exp Ther. 1992 Sep; 262(3):1168-72.
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Enhanced activity of the cardiac endocrine system during right ventricular hypertrophy. Mol Cell Endocrinol. 1989 Apr; 62(2):243-51.