"Peptide Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ligases that catalyze the joining of adjacent AMINO ACIDS by the formation of carbon-nitrogen bonds between their carboxylic acid groups and amine groups.
| Descriptor ID |
D010453
|
| MeSH Number(s) |
D08.811.464.259.850
|
| Concept/Terms |
Peptide Synthases- Peptide Synthases
- Synthases, Peptide
- Acid-Amino-Acid Ligases
- Acid Amino Acid Ligases
- Ligases, Acid-Amino-Acid
- Peptide Synthetases
- Synthetases, Peptide
|
Below are MeSH descriptors whose meaning is more general than "Peptide Synthases".
Below are MeSH descriptors whose meaning is more specific than "Peptide Synthases".
This graph shows the total number of publications written about "Peptide Synthases" by people in this website by year, and whether "Peptide Synthases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
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Below are the most recent publications written about "Peptide Synthases" by people in Profiles.
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Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control. 2010 Apr; 21(4):597-608.
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Recent advances in siderophore biosynthesis. Curr Opin Chem Biol. 2009 Apr; 13(2):205-15.
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The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retina. Mol Vis. 2006 Oct 26; 12:1292-302.
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Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs. J Biol Chem. 2003 Apr 25; 278(17):14926-35.
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Re: Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. J Natl Cancer Inst. 1999 Dec 01; 91(23):2047-50.
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Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration. Mol Pharmacol. 1999 Apr; 55(4):761-9.
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Effects of antisense-based folypoly-gamma-glutamate synthetase down-regulation on reduced folates and cellular proliferation in CCRF-CEM cells. Biochem Pharmacol. 1998 Jun 15; 55(12):2031-7.
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The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell. 1998 Apr 03; 93(1):103-9.
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Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res. 1995 Feb 01; 55(3):566-73.
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Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. Blood. 1994 Jul 15; 84(2):564-9.