In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL.

In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL. Cancer Gene Ther. 2006 Mar; 13(3):281-9.

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subject areas

Adenoviridae
Apoptosis
Apoptosis Regulatory Proteins
bcl-X Protein
CASP8 and FADD-Like Apoptosis Regulating Protein
Coxsackie and Adenovirus Receptor-Like Membrane Protein
Down-Regulation
Drug Synergism
Enzyme Inhibitors
Genetic Therapy
Histone Deacetylase Inhibitors
Hydroxamic Acids
In Vitro Techniques
Intracellular Signaling Peptides and Proteins
Membrane Glycoproteins
Receptors, Virus
TNF-Related Apoptosis-Inducing Ligand
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha
Urinary Bladder Neoplasms

authors with profiles

Christina Voelkel Johnson