E2F7 Transcription Factor
"E2F7 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F7 has two separate DNA-binding domains and binds to DNA independently of a dimerization partner.
Descriptor ID |
D050702
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MeSH Number(s) |
D12.776.930.211.968
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Concept/Terms |
E2F7 Transcription Factor- E2F7 Transcription Factor
- Transcription Factor, E2F7
- Transcription Factor E2F-7
- Transcription Factor E2F 7
- E2F Transcription Factor 7 Protein
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Below are MeSH descriptors whose meaning is more general than "E2F7 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F7 Transcription Factor".
This graph shows the total number of publications written about "E2F7 Transcription Factor" by people in this website by year, and whether "E2F7 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2005 | 0 | 2 | 2 |
2008 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2012 | 1 | 1 | 2 |
2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "E2F7 Transcription Factor" by people in Profiles.
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E2f8 mediates tumor suppression in postnatal liver development. J Clin Invest. 2016 08 01; 126(8):2955-69.
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Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer. Oncogene. 2017 02 09; 36(6):829-839.
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Canonical and atypical E2Fs regulate the mammalian endocycle. Nat Cell Biol. 2012 Nov; 14(11):1192-202.
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Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17; 22(4):849-62.
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Atypical E2Fs: new players in the E2F transcription factor family. Trends Cell Biol. 2009 Mar; 19(3):111-8.
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Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell. 2008 Jan; 14(1):62-75.
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E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene. 2005 Jul 21; 24(31):5000-4.
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Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem. 2005 May 06; 280(18):18211-20.
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Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem. 2003 Oct 24; 278(43):42041-9.