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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.

PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discov. 2015 Nov; 5(11):1194-209.

View in: PubMed

subject areas
  • Adaptor Proteins, Signal Transducing
  • Amino Acid Motifs
  • Animals
  • Binding Sites
  • Catalysis
  • Cell Line, Tumor
  • Disease Models, Animal
  • Enzyme Activation
  • Female
  • Heterografts
  • Humans
  • Mechanistic Target of Rapamycin Complex 2
  • Mice
  • Models, Molecular
  • Molecular Conformation
  • Multiprotein Complexes
  • Mutation
  • Neoplasms
  • Phosphatidylinositol Phosphates
  • Phosphorylation
  • Protein Binding
  • Protein Interaction Domains and Motifs
  • Proto-Oncogene Proteins c-akt
  • Proto-Oncogene Proteins p21(ras)
  • TOR Serine-Threonine Kinases

authors with profiles
  • Wenjian Gan