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Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase.
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Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase.
Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase. Mol Cancer Ther. 2018 12; 17(12):2710-2721.
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PubMed
subject areas
Animals
Cell Line, Tumor
Cell Proliferation
Cell Survival
Drug Resistance, Neoplasm
Drug Synergism
Glutathione
Humans
Male
Mice, SCID
NF-E2-Related Factor 2
Oxidation-Reduction
Phosphatidylinositol 3-Kinases
Protein Kinase Inhibitors
Protein Stability
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins c-pim-1
Reactive Oxygen Species
Ubiquitination
Up-Regulation
authors with profiles
Andrew S Kraft