Sterol 14-Demethylase

"Sterol 14-Demethylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Definition   |   Details   |   More General Concepts   |   Related Concepts   |   More Specific Concepts
An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols such as lanosterol. The enzyme acts via the repeated hydroxylation of the 14-methyl group, resulting in its stepwise conversion into an alcohol, an aldehyde and then a carboxylate, which is removed as formic acid. Sterol 14-demethylase is an unusual cytochrome P450 enzyme in that it is found in a broad variety of organisms including ANIMALS; PLANTS; FUNGI; and protozoa.


expand / collapse publications
Timeline   |   Most Recent
This graph shows the total number of publications written about "Sterol 14-Demethylase" by people in this website by year, and whether "Sterol 14-Demethylase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
_